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The clinical effects analysis of Pidotimod particle therapy in children with recurrent respiratory tract infections

HUANG Guohua;LU Shuanglong;Department of Paediatrics, Tongji Hospital;  
Objective: To analyze the treatment effects of Pidotimod particles clinical on children with recurrent respiratory tract infections. Methods: A total of 64 cases of repeated respiratory infection were selected from June 2012 to June 2013 admitted to hospital and randomly divided into conventional treatment group and conventional treatment + Pidotimod group. The symptoms, the immunity level and efficacy of two groups were compared before and after treatment. Results: The total efficiency of the conventional treatment + Pidotimod group(90.6%) was significantly higher than conventional treatment group(62.5%), the difference was statistically significant(P0.05). Antifebrile time of conventional treatment + Pidotimod group was(3.71±1.03) d, cough time(4.28±2.83) d, pulmonary rales disappeared time(4.96±2.16) d; Antifebrile time of the conventional treatment group was(5.32±0.96) d, cough time(8.77±2.47) d, pulmonary rales disappeared time o(6.21±1.98) d. The differences of Antifebrile time, cough time and pulmonary rales disappeared time between two group were statistically significant(P0.05). At the end of treatment, the level of Ig G, Ig A, Ig M and CD4+/CD8+ ratio of two group increased significantly, and the the increased change of the conventional treatment + Pidotimod group were greater than the conventional treatment group(P0.05). Conclusion: Pidotimod particles have obvious advantages in the treatment of recurrent respiratory tract infections, and can achieve better clinical results with conventional symptomatic treatment.
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