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《Journal of Clinical and Pathological Research》 2015-01
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Tristetraprolin and cancer

DING Weike;XIANG Lei;ZHANG Xiaorong;TU Jian;Institute of Pharmacy and Pharmacology,University of South China;  
Tristetraprolin(TTP),as a most common AU-rich element(ARE) binding protein,affects the mRNA stability and the protein expression through regulate the ARE acting element on 3' untranslated region(3'-UTR) of mRNA.The recent study shows that TTP have a further relationship with the tumorigenesis,development and prognosis of different cancer,like breast cancer,colon cancer etc.It strongly suggests that take a further study on TTP will make a great contribution to the cancer pathological diagnosis and treatment.
【Fund】: 国家自然科学基金青年项目(81100213);; 湖南省大学生创新性实验计划项目(2012cshncx5);; 衡阳市科技局课题(2013KJ22);; 湖南省十二五重点学科建设项目共同资助~~
【CateGory Index】: R730.2
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