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《Journal of Clinical and Pathological Research》 2015-03
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Recent progress of research on molecular mechanism of transcription factors in epithelial mesenchymal transition

GUO Peng;DONG Dongdong;WANG Jing;XU Jianfa;FENG Helin;Department of Orthopedics,the Fourth Affiliated Hospital of Hebei Medical University;Department of Urinary Surgery, the Fourth Affiliated Hospital of Hebei Medical University;  
The transdifferentiation of epithelial cells into motile mesenchymal cells was known as epithelial-mesenchymal transition(EMT). This switch in cell behavior has been illustrated to be mediated and closely related by some key transcription factors, including SNAIL, zinc-i nger E-box-binding(ZEB) and basic helix–loop–helix transcription factors(TWIST). This article reviewed the research of recent progress of transcription factors the related mechanism of EMT.
【Fund】: 河北省自然基金面上项目(H2015206314)~~
【CateGory Index】: R730.2
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