Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Clinical and Pathological Research》 2015-07
Add to Favorite Get Latest Update

The expression of P504S in prostate adenocarcinoma, renal cell carcinoma and bladder urothelial carcinoma and its clinical significances

MA Zhiwei;DONG Dandan;GONG Baisheng;QIU Mingxing;Department of Urology,Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital;Department of Pathology, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital;  
Objective: To evaluate the expression and clinical significance of P504 S in prostate cancer(Pca), renal cell carcinoma(RCC) and bladder transitional cell carcinoma(BTCC). Methods: Immunohistochemical labeled dextran polymer(LDP) methods were used to detect the expressions of P504 S in Pca, RCC and BTCC, and also to analyze the difference of expressions in benign prostatic hyperplasia tissue, normal renal tissue and normal bladder tissues. Results: The positive expression rates of P504 S in Pca, RCC and BTCC tissues were 93.10%, 65.28% and 46.07% respectively, but in BPH tissue, normal renal tissue and normal bladder tissue were 0%, 6.67% and 6.25% respectively, the expression was significantly different(P0.01). The positive expression levels of P504 S were positively correlated to tumor pathological grades and tumor clinical stages(P0.05) of Pca, RCC and BTCC. It was also closely correlated with the prognosis of tumor. Conclusion: It suggested that P504 S might play a role in the biological behavior of Pca, RCC and BTCC and might serve as an important indicator of the invasion, development and prognosis of these tumors.
【Fund】: 四川省甲级重点学科(泌尿外科)建设项目(2015)~~
【CateGory Index】: R737
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved