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《Journal of Clinical and Pathological Research》 2015-07
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A clinicopathological study of angiolymphoid hyperplasia with eosinophilia

ZHOU Bingjuan;ZHANG Nan;SUN Jirui;ZHAO Wenming;ZHANG Jinku;Pathology Department,the first Central Hospital of Baoding;Dermatology Department, the first Central Hospital of Baoding;  
Objective: To investigate the clinicopathologic features, immunophenotypes and differential diagnosis of angiolymphoid hyperplasia with eosinopilia(ALHE). Methods: Three cases of ALHE were evaluated by the clinical and pathological characteristics and the immunohistochemical stain(IHC). Results: In these cases, two patients were female and one was male. Histopathologically, they presented as a nodular lesion in the skin of head and neck region and the histopathological appearance of these cases were characterized by numerous thick and thin-walled vessels lined by characteristic epithelioid endothelial cells. Prominent inflammatory infiltrate including eosinophils, lymphocyte and plasma cells could be presented surrounding the vessels. Th immunohistochemistry revealed the positivity of these epithelioid endothelial cells for CD34, CD31 and CD3, the negative for CD20 and CK. Conclusion: ALHE is a rare benign vascular lesion and the diagnosis mainly depends on histopathological characteristics.
【CateGory Index】: R732.2
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