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《Journal of Xi'an Jiaotong University(Medical Sciences)》 1988-01
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EFFECTS OF RESERPINE ON AURICLE OF GUINEA PIG

Zhao Dongke, et al (Department of Pharmacology)  
Effects of reserpine on the physiologic properties of myocardium were studied in the auricle of quinea pig. Reserpine (10 μM) decreased the contractive force of the left auricle to 57 ±15% (P0.01) and the frequency of the right auricle from 147±10 beats per minute to 120 ±20 beats per minute (P0.01). It also decreased the epinephrine-induced automaticity and prolonged the functional refractory period from 183±14ms to 206±7 ms, while It did not change the duration-intensity curve (P0.05) in the left auricle of guinea pig, Reserpine shifted the dose-response curve of epinephrine positive frequency non-parallelly to the right with decrease of its maximum effect. It also possessed antagonistic effect for calcium positive frequency response. The results obtained indicate that reserpine might possesse calcium antagonistic effect.
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【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Huang Renbiao Tutor: Prof. Lo Qian (Lo Sing) (Dept. of Pharmacology);The Effects of Some Free Radical Scavengers on Ouabain—induced Arrhythmias in Guinea Pigs——Free Radicals May be Involved in the Toxicity of Digitalis[J];Journal of Jinan University;1989-04
2 Zhao Dongke, et al (Department of Pharmacology);EFFECTS OF DL-TETRAHYDROPALMATINE ON ACTION POTENTIALS AND CONTRACTILITIES OF GIUNEA PIG PAPILLARY MUSCLES AND ITS LOCAL ANESTHETIC ACTION[J];Journal of Xi'an Jiaotong University(Medical Sciences);1986-03
3 Zhao Dongke,et al (Department of Pharmacology);COMPARISON OF THE EFFECTS OF RESERPINE WITH VERAPAMIL ON THE LEFT AURICLE OF GUINEA PIG[J];Journal of Xi'an Jiaotong University (Medical Sciences);1989-03
4 Li Le, Zhuang,Feier Zhao Gengsheng(Department of Pharmacology);EFFECTS OF OSTHOLE ON THE PHYSIOLOGICAL PROPERTIES IN THE ISOLATED AURICLE OF GUINEA PIG[J];Journal of Xi'an Jiaotong University(Medical Sciences);1992-03
5 Ma Xin;Yu Li;Luo Guangwei, et al Department of Pharmacology;NEGATIVE INOTROPISM OF THE EFFECT OF FeSO_4 ON ISOLATED GUINEA PIG HEART ATRIUM[J];Journal of Xi'an Jiaotong University(Medical Sciences);1993-01
6 Zhao Dongke, Zhao Gengsheng & Qiu Peilun (Dept. of Pharmacology, Xian Medical University, Xian);EFFECTS OF DL-TETRAHYt)ROPALMATINE ON THE AURICLE OF GUINEA PIG[J];Chinese Pharmacological Bulletin;1987-02
7 Sun Feng & Li Dexing ( Dept. of Pharmacology, Nanjing Medical College);EFFECTS OF L-TETRAHYDROPALMATINE ON ISOLATED GUINEA PIG ATRIA[J];Chinese Pharmacological Bulletin;1989-03
8 Li Husong & Zhao Gengsheng ( Dept. of Pharmacology, Xian Medical University, Shanxi);EFFECT OF 4-PHOSP ATE-HYDROXYPIPERAQUINE ON THE ISOLATED AURICAL OF GUINEA PIG[J];Chinese Pharmacological Bulletin;1989-03
9 Ma Xin, Li Xiaoguang (Research Laboratory of Electrophysiology, Xian Medical University, Xian 710061);NEGATIVE INOTROPIC EFFECT OF ZINC SULFATE IN ISOLATED GUINEA PIGS ATRIA[J];Chinese Pharmacological Bulletin;1990-05
10 PU HanLin,WANG ZhengLian,HUANG QiaoJuan,XU ShiBo,LIN YongCheng1,WU XiongYu1 (Dept of Pharmacy, 1School of Chemistry and Chemical Engineering,Zhongshan University, Guangzhou 510275);Effects of biatractylolide on isolated guinea pig myocardium[J];CHINESE PHARMACOLOGICAL BULLETIN;2000-01
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