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《Journal of Xi'an Medical University(Chinese)》 2003-01
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Study of dobutamine combined with nitroglycerin echocardiography in identifying viable myocardium of patients with myocardial infarction

Chu Wen (Ultrasonic Department, Luoyang Central Hospital, Luoyang 471009, China)  
Objective To evaluate the accuracy and safety of dobutamine combined with nitroglycerin echocardiography in identifying viable myocardium of patients with myocardial infarction (MI). Methods Dobutamine and dobutamine combined with nitroglycerin echocardiography were performed in 29 patients with MI to detect the regional wall motion before coronary revascularization. The regional wall motion was detected again about 3 months after operation. According to the actual contractile improvement of regional wall motion of postoperation,the sensitivity, specificity and accuracy of the tests for identifying viable myocardium were calculated.Results The sensitivity, specificity and accuracy of the tests for identiifying viable myocardium were 90.9%, 95.6%, 96.2%, respectively. The sensitivity of dobutamine combined with nitroglycerin echocardiography increased compared with that of dobutamine echocardiography, although no statistical significance was found, while no effects were found in the specificity and accuracy of the tests. A significant decrease of WMSI was found in 10?μg·kg -1·min -1 dobutarmine combined with nitroglycerin echocardiography compared with 5?μg·kg -1·min -1 dobutamine (P0.05), but there was no significant decrease of WMSI in 10?μg·kg -1·min -1 dobutamine alone compared with 5?μg·kg -1·min -1 dobutamine (P0.05). No occurrence of ischemia was found in 10?μg·kg -1·min -1 dobutamine combined with nitroglycerin echocardiography as induced in 10?μg·kg -1·min -1 dobutamine alone. Conclusion Dobutamine combined with nitroglycerin echocardiography in identifying the viable myocardium of patients with MI have more sensitivity and safety compared with dobutamine alone.
【CateGory Index】: R445.1
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【Citations】
Chinese Journal Full-text Database 1 Hits
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【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 HUANG Chao-lian,FANG Li-gang;Treatment of chronic total occlusion of coronary artery[J];Basic Medical Sciences and Clinics;2001-02
2 YANG Songna, ZHOU Huiqing , WANG Weimin, et al. Department of Cardiology,People's Hospital,Peking University, Beijing 100044, China [;Detection of viable myocardium by sublingual nitroglycerin echocardiography[J];Journal of Clinical Internal Medicine;2001-04
3 YE Xue-cun, FENG Li-li, GE Yu-zhi (Department of Cardiovascular Reseach, Jiangxi People's Hospital, Nanchang Jiangxi 330006, China);Value of Pharmacologic Stress Echocardiograply in Diagnosis of Coronary Heart Disease[J];Chinese Journal of Medical Physics;2004-06
4 GUO Ruiqiang,BAI Jing,HAO Lidan,et al.Department of Ultrasonography,the First Affiliated Hospital of Hubei Medical University,Wuhan 430060,China;The value of low-dose dobutamine stress echocardiography in detecting survived myocardium[J];Chinese Journal of Uitrasonography;2000-11
5 FANG Li-gang CHEN Li-bo LI Fang ZHU Wen-ling FANG Quan. Department of Cardiology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;Comparision of low-dose dobutamine echocardiography and dual-isotope emission simultaneous myocardial perfusion acquisition for myocardial viability assessment[J];Chinese Journal of Cardiology;2007-04
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