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《Journal of Xi'an Jiaotong University(Medical Sciences)》 2015-01
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In-hospital mortality and cardiovascular outcomes in myocardial infarction patients with or without first-time heart failure

DENG Fu-xue;WANG Xiao-juan;HU Yun-feng;CHANG Jing;Department of Cardiology,the First Affiliated Hospital of Chongqing Medical University;Department of Public Health,Medical School of Xi'an Jiaotong University;  
Objective To examine factors that affect incidence,in-hospital treatment,major cardiovascular events(MACEs)and short-term mortality in patients hospitalized for acute myocardial infarction(AMI)newly complicated with heart failure(HF). Methods The baseline characteristics,treatment patterns, major cardiovascular events,and in-hospital mortality were examined in 591 AMI patients complicated with first-time HF who were admitted in our hospital between February 2009 and December 2012.Results Among these 591 AMI patients,222 were complicated with HF and369 patients were without HF.It was found that patients with HF were less likely to be examined by cardiac angiogram[(56.3∶73.4)%]or treated with reperfusion therapy[(43.2∶62.9)%]and medications recommended by ACCF/AHA for HF.And they had a greater risk for in-hospital mortality[(15.3∶2.4)%]than non-HF patients.In addition,HF(OR =2.97)and cardiogenic shock(OR =7.53)complicating AMI were strongest predictors of in-hospital death.Conclusion Patients with new and first-time HF complicated with AMI are at a higher risk for adverse in-hospital outcomes.Accurate and rapid diagnosis and timely and comprehensive treatment such as reperfusion and recommended medication can significantly lower the shortterm mortality rate.
【Fund】: 国家临床重点专科建设项目经费资助(财社[2011]170号)~~
【CateGory Index】: R542.22;R541.6
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