Variations of Fibroblast Growth Factor Receptor 1(FGFR1) Gene in Normal Mouse Heart Tissue
Wang Ping, Yu Yongli(Department of Immunology, Norman Bethune University of Medical Sciences,Changcun 130021)
The cDNA of FGFR1 extracellular part was taken out from human lung fibroblast by RT PCR. After labelled with digoxin, the FGFR1 extracellular part cDNA was used as a probe in the Southern blot analysis of the Sal Ⅰ digested genomic DNA from mouse heart and other tissues. The results indicated that the Southern blot band pattern of adult mouse heart was changed, when compared with the other tissues. Three possible mechanisms of this change were proposed.