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《Chinese Journal of AIDS & STD》 2010-02
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Analysis of the follow-up results of suspected congenital syphilis in four cities

LONG Fu-quan, WANG Qian-qiu, YANG Ping, et al.( Institue of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042,China)  
Objective To analyze the follow-up results of suspected congenital syphilis cases in cities of Huizhou, Sanya, Qionghai and Yuhang from January 2007 to December 2008. Methods Sixty-three suspected congenital syphilis cases in the four cities were followed up by detecting TPPA and RPR titers. The results were analyzed by statistical software SPSS 13.0. Results All 63 cases with suspected congenital syphilis were TPPA positive, and the RPR titer ranged from negative to 1:64, of which 27cases were followed up for one to four times, and the rate of follow-up was relatively high in two cities of Hainan province ( i.e. Sanya and Qionghai ). Forty-two cases were treated with penicillin, of which 18 cases were followed up for 3-12 months and 15 cases reported significant improvement with a rate of marked efficacy of 88.33% , while 21 cases were not treated ,of which 9 cases were followed up for 3 months, with a rate of marked efficacy of 22.2% The rate of improvement after the treatment was 62.96%. The treated cases were more likely to achieve improvement than those without treatment (χ2=7.14, P0.01). Conclusions Treatment with penicillin promptly after birth will lead to a better efficacy, and regular follow up for infants of suspected congenital syphilis will play a very important role . It is suggested that health care providers be trained in standardized management of suspected congenital syphilis in order to increase the rate, frequency and duration of follow-up.
【Fund】: 科技部科研院所社会公益研究专项基金(2005DIB1J096)~~
【CateGory Index】: R759.1
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