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Adverse drug reactions of ceftriaxone

ZHANG Chunling,YAO Hong,CHANG Yu(Department of Pharmacy,The Affiliated Red Cross Hospital,College of Medicine,Xi'an Jiaotong University,Xi'an 710054,China)  
Objective To explore the types of adverse drug reactions of ceftriaxone and their corresponding mechanism.Methods CNKI,VIP,Pubmed,and OVID databases about ceftriaxone side effects,adverse reaction mechanism and corresponding measures for the prevention of treatment-related reports were analyzed retrospectively.Results Ceftriaxone may cause allergic reactions,allergic shock,gastrointestinal adverse reactions,urinary side effects,adverse reactions blood system,and nervous system adverse reactions.Part of the adverse reactions were caused by different administration route,overdose,or drug compatibility unreasonable result.Conclusion By adverse drug reactions and mechanism analysis,reasonable application of ceftriaxone sodium,could be attained in clinical.
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