Full-Text Search:
Home|About CNKI|User Service|中文
Add to Favorite Get Latest Update

The analysis of liver dysfunction induced by vancomycin

SUN Tao;YANG Mengmeng;YANG Peng;ZHENG Yao;ZHANG Yan;Department of Pharmaceutics,Tangdu Hospital,the Fourth Military Medical University;  
Objective To investigate the inpatients of liver dysfunction induced by vancomycin for promoting the rational use of vancomycin.Methods The patient cases using vancomycin were gathered from August 2015 to July 2016 and the patient basic information,drug use and liver function were statistically analyzed.Results 980 inpatients were intravenously dripped vancomycin for 5.55±2.25 d,liver dysfunction occurred in 13 inpatients(AST:85.18±50.77 U·L~(-1),ALT:141.00±86.26 U·L~(-1)).The incidence rate was 1.33%.The liver function was recovered(AST:37.55±27.79 U·L~(-1),ALT:47.09±26.56 U·L~(-1))after stop using vancomycin 5.15±1.29 d.Conclusion The liver dysfunction induced by vancomycin was common.Therefore,the changes of liver function must be monitored during the using of vancomycin for ensuring safe usage of medicine and avoiding doctor professional risk.
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©CNKI All Rights Reserved