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Development of Researches on Electroacupuncture Treatment of Depression in Recent 10 Years

LU Jun, HAN Zhi-rong, SHI Yu-jing, TU Ya (College of Acu-moxibustion, Beijing University of TCM, Beijing,100029)  
In the present paper, the authors review development of researches on electroacupuncture (EA) treatment of depression from 1) clinical therapeutic effect: a) comparison between EA and antidepressant, b) comparison between EA combined with antidepressant and simple antidepressant, c) comparison between EA combined with antidepressant and simple EA, d) comparison between EA and filiform needle; 2) researches on the underlying mechanisms of EA in the treatment of depression: a) clinical studies, and b) experimental studies. Clinical studies indicate that EA may improve depression patients' immune function and regulate levels of T cells, activity of IL-2, IL-1β, IL-6, TNF-α, etc. and experimental researches show that monoamines neurotransmitters and their receptors, hypothalamus-pituitary anterior lobe (HPA)-axis, brain-derived neurotrophic factor, etc are involved in the effect of EA in improving depression.
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