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《Chinese Journal of Tissue Engineering Research》 2018-31
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Application of trabecular tantalum cage in anterior cervical discectomy and fusion for cervical spondylosis and its anatomical characteristics

Huang Ming-zhi;Zhuang Yong;Zhang Hao;Shang Xian-wen;Department of Orthopedics,the Affiliated Hospital of Guizhou Medical University;  
BACKGROUND: Trabecular tantalum cage plays an important role in anterior cervical discectomy and fusion(ACDF) for cervical spondylosis, but its anatomical morphology remains controversial. OBJECTIVE: To investigate the effect and anatomical characteristics of trabecular tantalum cage in ACDF for patients with cervical spondylosis. METHODS: Ninety-three patients with cervical spondylosis were enrolled, and underwent ACDF using bone autograft(n=31, autograft group), polyether ketone cage combined with bone autograft(n=31, polyether ketone group) or trabecular tantalum cage combined with bone autograft(n=31, trial group). The perioperative complications were recorded. Before and 6 months after treatment, the Visual Analogue Scale, Japanese Orthopedic Association, Neck Disability Index, intervertebral fusion, intervertebral space height, and anterior lordosis of fused segment on CT were detected. RESULTS AND CONCLUSION:(1) There was no difference in the incidence of complication among groups.(2) The Visual Analogue Scale, Japanese Orthopedic Association, and Neck Disability Index scores at 6 months after treatment in each group were significantly improved compared with baseline(P 0.05). The Japanese Orthopedic Association, and Neck Disability Index scores at 6 months after treatment in the autograft and trial groups were significantly improved compared with the polyether ketone group(P 0.05), and the scores showed no significant difference between autograft and trial groups. The Visual Analogue Scale scores at 6 months after treatment did not differ significantly among groups.(3) The intervertebral space height, anterior lordosis of fused segment, and fusion area at 6 months after treatment in each group were significantly improved compared with baseline(P 0.05). The imaging indexes in the autograft and trial groups were significantly improved compared with the polyether ketone group(P 0.05), but showed insignificant difference between autograft and trial groups.(4) At 6 months after treatment, the fusion rate in the trial group was significantly higher than that in the autograft and polyether ketone groups(P 0.05).(5) These results imply that trabecular tantalum cage applied in ACDF obtains satisfactory outcomes, and can achieve cervical reconstruction and good stability, which is accordance with the anatomical requirements.
【Fund】: 贵州省科技厅项目[黔科合LH字(2014)7111]~~
【CateGory Index】: R687.3
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