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《Modern Scientific Instruments》 2008-06
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Study on the Recognition Property of Molecularly Imprinted Polymers with Methyltestosterone as Template

Shen Ruilian~1 Yang Minli~2 Yong Wei~2 Chen Zhengxing~3 Wang Daning~2 Chu Xiaogang~2 (1 State.Key Laboratory of Food Science and Technology,Wuxi 214122) (2 Institute of Food Safety,Chinese Academy of Inspection and Quarantine,Beijing 100123) (3 School of Food Science and Technology,Jiangnan University,Wuxi 214122)  
A methyltestostemne-imprinted polymer was prepared under the condition of thermal-initiation through a molecular imprinting technology,with MAA as functional monomer and EGDMA as cross-linker.The affinity of the MIP as solid phase for the template and its structural analogs was studied.The influence of the mobile phase u- sing different vohnne fractions of water in the acetonitrile on the retention behavior was also discussed.In addition,e- quilibrium binding experiments were carried out to evaluate the adsorption properties and selective recognition ability of the MIPs.The results showed that,the MIPs exhibited high selectivity and recognition ability to the template.
【Key Words】： methyltestosterone molecularly imprinted polymers recognition HPLC
【Fund】： 国家863专题课题：主要禁用兽药的分子印迹技术研究(2006AA10Z435)
【CateGory Index】： O631.3
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