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《Journal of Xiamen University(Natural Science)》 2010-01
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Study on the Quality Standard and Stability for Deacetylmycoepoxydiene

XU Ying,HUANG Yao-jian,ZHANG Lian-ru~*, HUANG Huan,ZHENG Zhong-hui,SHEN Yue-mao (School of Life Sciences,Xiamen University,Xiamen 361005,China)  
Deacetylmycoepoxydiene has been proved to be a new and promising anticancer drug by pharmacology and toxicology.By means of influential factor experiment,accelerating experiment and long-term experiment,using the techniques of HPLC,IR,UV and thermal gravitational analysis,the character,identification,purity investigation,content determination and the stability for light,heat of deacetylmycoepoxydiene was studied.And the standard for qualith of deacetylmycoepoxydiene was set up.The stability experiment showed that deacetylmycoepoxydiene has a good stability under the harsh condition of high temperature,high moisture and violet light.The results suggested that deacetylmycoepoxydiene can be stored at airtight and common temperature conditions.This study laid the foundation for open and development deacetylmycoepoxydiene in industrialization.
【Fund】: 国家863计划(2007AA091503);; 厦门市科技项目(3502Z20093014)
【CateGory Index】: Q936
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