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The Malignant Mixed Mesodermal Tumors of Female Genital Tract (Clinical Analysis of 29 Cases)

Wu Junping;Zhang Xiyin(Gynecological &. Obsieirical Hospilal of Shanghai Medical Uniuersity, Shanghai 200011)  
Although the incidence of the malignant mixed mesodermal tumor in female genital tract is low. the malignancy is of high grade. 29 cases of the malignant mixed mesodermal tumors of the female genital tract in the Gynecological and Obstetrical Hospital of Shanghai Medical University were presented in this paper from 1965 to 1 993,of them, 20 cases from endometrium, 2 from cervix, 6 from ovary, 1 from fallopian tube- They occupied about 0. 3 % of all patients hospitalized in gynecological department, and about 5. 9 %. of all gynecological oncological patients during the same period in the hospital. The clinical manifestations were vagina bloody disoharge (74. 4% ) and aboominal pain (27. 6 % ). Diag nostic curettage is helptul to diagnosis for the patients with vagina bloedy discharge preoperativeIy, the success rate is 71 %. But it was insignificance in the patients without these symptoms. The prognosis of the tumor was poor, which 12 of 29 patients died within two years, only 7 of 29 patients lived more than five years. The prognosis of the malignant mixed rnesoclermal tumor of uterus may be better than the tumor of other fernale genital organs. The survival rate of five years is higher in patients after a complete surgery than those af-ter hyserectomy and bisalpingo-oophorectomy only. The effectiveness of chemotherapy is uncertain, but the use of the combined chemotherapy of the long-term, mainly in DDP, may lead to complete or partial remission.
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