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《Zhejiang Cancer Journal》 1995-01
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The Detection of ER、PR in Uterine Myoma, Adenomyoma and Peripheral Blood Leukocyte of the Patients

Liu Zhihua; Cai Guiru (Tongji Hositai, Tongji Medicai Uniuersily, Wuhan 430030)  
In this article, we made a comparative study on relationship of the uterine myoma and edenomyoma with the estradiol and pro-geserone. The results showed that in myoma and adenomyoma, estradiol receptor (ER) positive tate was significantly higher than those in control group (p0. 01, p0. 05 ), Progesterone receptor (PR ) positive rate was below the control group, only in adenomyoma PR leve was significantly lower than those in control group (p0. 05). In peripheral blood leukocyte Of petients with myoma or adenomyoma and normal women, there was no significant difference in ER, PR status. In addition, serum E2 P leves were also aaseyed. Serum E2 of the patients with myoma or adenomyotna was significantly higher than normal women in follicular phase (p0. 05, p0. 01). Serum P of the patients with myoma was significantly lower than normal women. Tbe results suggested that the imbalanec of estradiol and Progedetone in serum and tumor might be responsible for occurring and development of myoma or adenomyoma. The high E2 level in serum and tumor may inhibit the patient's immune function and may be also influence tumor devefopment.
【CateGory Index】: R737.33
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【Citations】
Chinese Journal Full-text Database 4 Hits
1 Xu Lan and He Shirong(Department of Obstetrics and Gynecology, First Teaching Hospital, Third Military Medical College);Relationship between Cytosol Estrogen Receptor Level in Uterine Leiomyoma and Sex Steroid Level in Plasma, Leiomyoma and Myometrium[J];Acta Academiae Medicinae Militaris Tertiae;1986-03
2 Xia Wenjia,Li Yu,Tan Daiyin,Su Nan,Yu Dunqui,Wu Changjie,Sun Xuedong,Wu Xirui Family Planning Research Institute,Tonji Medical University,Wuhan;Radioimmunoassay of 7 Hormones in Serum During Menstrual Cycles of Normal Women of Reproductiveage in Wuhan[J];Journal of Tongji Medical University;1986-06
3 Niu En-mei;DETERMINATION OF CYTOPLASMIC ESTROGEN AND PROGESTERONE RECEPTORS IN LEIOMYOMA AND ADENOMYOSIS OF UTERUS[J];Tumor;1986-02
4 Liu Shang-lian;DETECTION OF ESTROGEN RECEPTOR IN BREAST CARCINOMA BY THE ENZYME-LABELLED ESTRADIOL HISTOCHEMICAL METHOD[J];Tumor;1986-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SU Ning HAN Yue-ming ZHANG Xiao-ming ZHANG Rui-ying (Department of Pathology, Nanjing Railway medical College, Nanjing);A STUDY ON HISTOGENESIS AND HORMONE-DEP ENDENCE OF BREAST CARCINOMA INDUCED BY DMBA IN RATS[J];Chinese Journal of Cancer;1990-01
2 LU Liang yong1*, LIU Shang lian2, HUANG Wei da3, YANG Guang cai1 CHEN Cheng wei1, LI Xiao yan1, JIANG Shu juan4, WEI ying4 1.Department of Molecular Pathology, Department of Pathology, 85 Hospital of PLA, Shanghai 200235, P.R.China 2.Depart;Clinical Significance and Prognosis of ER mRNA PR mRNA Postive Expression in Breast Carcinoma[J];Chinese Journal of Cancer;2001-11
3 Tao Xiaojing,He Shirong (Department of Obsterics and Gynecology, Southwest Hospital, Third Military Medical College,Chongqing,630038);A study on the concentration of cytosol receptors for estrogen,progestin,and androgen in human uterus[J];Acta Academiae Medicinae Militaris Tertiae;1992-05
4 Huang Li, Wang Ling (Electron Microscopy Department of Nanjing Medical University, China, 210029);The Use of Microwave Irradiation in Electron Microscopy for Estrogen Receptor Localization in the Cell[J];;1995-01
5 WU Hua,CAO Jun,YU Zhong hua,et al (Department of Oncology,A ffiliated Hospital of Guangdong Medical College,Zhanjiang 524001);Expression of p53,C-erbB-2 and nm23 genes and estrogen ,progestogen receptors in breast cancer and their clinical significance[J];Journal of Guangdong Medical College;2002-04
6 Dai jie, et al.(Department of Pathology, Zhangjiakou Medical College, Zhangjiakou 075000);IMMUNOHISTOCHEMICAL STUDIES OF ER. PR AND CEA IN THE GASTROCOLIC TUMORS[J];CHINESE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY;1995-03
7 Liu Jianlun; Yang Nanwu;Wei Changyuan;et al(Department of Surgery’the Affiliated Tumour Hospital);THEK ELATIONSHIP BETWEENESTROGEN KECEPTORANDCELLULAKIMMUNITYIN PATIENTSWITHADVANCED GASTRICCANCER[J];ACTA ACADEMIAE MEDICINAE GUANGXI;1995-01
8 Yang Zhulin Xu Jianfuang Yang Yuanhua Laboratory of Hepatobiliary Diseases,The Second Affiliated Hospital,Hunan Medical University;EXPRESSIONS OF ER,PgR,γ-GT,LDH AND THEIR RELATIONSHIP IN HUMAN BREAST CANCER[J];Bulletin of Hunan Medical University;1994-03
9 Chen Dong; Wei Li;Chen Zhenguang; Li XinrOng;He Jianyie;Wang Yuping;Zhang Lei (Department of Pathology,Henan Medical University, Zhengzhou 450052 Department of Surgery,Zhengzhou Railroad Central Hospital, Zhengzhou 450052 Department of Pathology,the Third;Assay of estrogen and progesterone receptors in endometrial hyperplasia and adenocarcinoma of endometrium[J];JOURNA OF HENAN MEDICAL UNIVERSITY;1995-03
10 LI Ye, WANG Xiao-ying, JIN Xiao-long, XU Hai-min, (Department of Pathology, RuiJin Hospital, Shanghai Second Medical University, Shanghai 200025, China);Expression of C-erbB-2 gene, Multidrug-resistance Gene (P-gp) and Their Interrelationship to ER, PR in Human Breast Cancer[J];Hunan Medical Journal;2002-04
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 Niu En-mei;Cai Gen-sheng;Tang Zhen-hua International Peace Maternity and Child Health Hospital, Shanghai, China;CYTOPLASMIC ESTRADIOL AND PROGESTERONE RECEPTORS IN HUMAN ENDOMETRIUM WITH NORMAL MENSTRUAL CYCLES (116 Cases)[J];Reproduction & Contraception;1984-02
2 Yao Lian-sheng;Zhou Jian-liang;Tang Jin-xia;Zhang Xin-di Shanghai Institute of Biochemistry, Academia Sinica Cancer Hospital, Shanghai First Medical College;ESTIMATION OF NUCLEAR ESTROGEN RECEPTOR FOR 99 CASES OF MAMMARY TUMORS[J];Tumor;1981-06
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