A Study on the Expression of Granulocyte-relative Antigen in Gastric Carcinoma and the Tissues around it
Zhou Tao; Ye Min; Chen Hansong; et al (Taizhon Hospital,zhejiang 317000)
Granulocyte relative antigen (CD15 ) is known as Leu M1, as well. It is mainly found in the R-S cells of patients with Hedgkin's disease. Taking advantage of antibody of CD15 in the examination of 65 cases suffering from gastric carcinoma,we found that the Positive expression rate of gastric cancer is 66. 15 % (43/65 ) in the gastric carcinoma and the tissues around it,however,the dysplasia around it is 54. 76 % (23/42 ). But the expression of the normal gastric pit of epithelial cells is negative. Obviously, the former two groups are signlficant-ly differentiated frorn the latter (p0.05 )Of the 65 cases, tbe positive rate is the highest in tubular adenocatcinoma (bigh and medium differentiation) (88. 46 % ); the poor differ-entiated adenocarcinotnais (61. 11%); the positive rate the mucinous adenocarcinoma is the second (50 % ):and the signetring cell carcinoma is the lowest (36. 36 % ).