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Trapa Extract Induced Apoptosis in Liver Cancer Cell Line SMMC-7721

XIE Yan-ru(Lishui Central Hospital,Lishui 323000,China)  
[Purpose] To investigate the anti-cell proliferation effect with Trapa extract in liver cancer cell line SMMC-7721.[Methods] The inhibition effect was detected by MTT method.Apoptosis was detected by AO staining,DNA agarose gel electrophoresis and FCM.[Results] The growth of SMMC-7721 cells was inhibited and cell apoptosis was induced by Trapa extract in a dose-dependent manner.Typical morphological changes of apoptosis were observed by fluorescence microscopy.[Conclusion] Trapa extract can inhibit proliferation and induce apoptosis in liver cancer cell line SMMC-7721.
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