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《Journal of Chinese Oncology》 2012-01
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Monitoring of Setup Error Measurement and Variationtrend During IMRT for Nasopharyngeal Carcinoma

LIN Liu-wen,GAO Li-juan,HUANG Qun-feng,et al.(Cancer Center,Sun Yat-sen University,Guangzhou 510060,China)  
[Purpose] To analyze the setup errors and the body weight trends of the nasopharyngeal carcinoma(NPC) patients during intensity modulated radiation therapy(IMRT) using the thermoplastic masks and individualized lengthen vacuum pads.[Methods] Twenty-three cases with NPC were treated with IMRT and carried out the electric portal image device(EPID) and body weighted once a week during the 6-week course of treatment.Previously,treatment machine calibration was also performed to ensure the accuracy of EPID system.Registration based on the EPID images and the Digitally Reconstructed Radiograph(DRR) images which were formed from CT scan in the treatment planning system,the values of group set-up errors and weekly differences was analyzed.Meanwhile,the effect of changes in body weight on setup errors was analyzed.[Results] Regardless of weekly differences,the setup errors in the lateral(RL),anteroposterior(AP) and superior-inferior(SI) directions was 0.165±0.121,0.064±0.122 and 0.038±0.135cm respectively.According to different week,the 6-weekly set-up errors in RL,AP,SI directions had no obviously significant differences(P0.05).Bivariate correlation analysis showed that the migration in three direction had no significant correlation with changes of body weight(r=0.147,P=0.152;r= 0.102,P=0.321;r=0.114,P=0.267).[Conclusion] There is good repeatability and accuracy in IMRT for NPC patients with individualized lengthens vacuum pads and thermoplastic masks.The change of body weight is no effect on set-up errors.
【Fund】: 广东省科技计划资助项目(2007B031516004)
【CateGory Index】: R739.63
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