Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Chinese Oncology》 2012-02
Add to Favorite Get Latest Update

A Meta Analysis of Adjuvant Therapy for Esophageal Cancer Postoperation

MAO Wei-min,CHENG Lei(Zhejiang Cancer Hospital,Hangzhou 310022,China)  
[Purpose] To investigate the value of adjuvant therapy for esophageal cancer postoperation.[Method] randomized control study articles about adjuvant treatment after esophagectomy from 1995 to 2011 were collected,and Stata12.0 software was used for Meta analysis.[Reasults] Compared with patients undergoing surgery alone,the 3-year progress free survival(PFS) in patients with adjuvant chemotherapy was significantly different,with RR 1.225(95%CI:1.012~1.482,P=0.037).But 3-,5-year overall survival rates(OS) with RR 0.899(95%CI:0.797~1.016,P=0.087) and 1.183(95%CI:0.97~1.442,P=0.098),respectively.3-year OS of adjuvant radiation patients was significantly different with that of the patients with surgery alone,RR0.935(95%CI:0.879~0.994,P=0.033).But 5-year OS with RR 0.988(95%CI:0.821~1.188,P=0.897).P values of Begg's and Egger test were greater than 0.05,indicating there was no publication bias in the study.[Conclusion] Postoperative adjuvant chemotherapy can improve the 3-year PFS in patients with esophageal cancer after surgery,while postoperative adjuvant radiation does not improve 3-year OS.
【CateGory Index】: R735.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved