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Long-term Response of Ultrasound-guided Percutaneous Microwave Ablation for Hepatocellular Carcinoma Adjacent to Vessels

YANG Xiao-huan;HUANG Shi-jia;YU Jie;Chinese PLA General Hospital;  
[Purpose] To investigate the effectiveness and safety of ultrasound(US)-guided percutaneous microwave ablation(MWA) in the treatment of hepatocellular carcinoma(HCC) adjacent to vessels. [Methods] US-guided percutaneous MWA was applied to 536 patients with 697 HCC nodules(vessels group:Group V,189 patients with 216 lesions;control group: Group C,347 patients with 481 lesions. During the ablation,the temperature of marginal ablation tissues was monitored and controlled. [Results] The median follow-up was 25.4 months(range 3.2 ~92.2months) in Group V,and 25.7 months(range 2.5~99.3 months) in Group C. Technical effectiveness was achieved in 207 of 216(96.2%) tumors in Group V and 465 of 481(96.8%) tumors in Group C,without significant difference between them(P=0.923). The 1-,3- and 5-year local tumor progression rates and the 1-,3- and 5-year accumulative survival rates in the two groups had no significant difference. In addition,no serious complications such as vessels or bile ducts injury were found in both of the two groups.[Conclusion] With strict temperature monitoring,US-guided percutaneous MWA is an efficient and safe technology for treating hepatocellular carcinoma adjacent to vessels.
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