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Clinical Response of Stereotactic Radiotherapy in 50 Cases with Primary Liver Cancer at Early Stage

LI Yu;ZHANG Su-jing;LIU Xiao-liang;General Hospital of PLA;  
[Purpose]To evaluate the short-term response and toxicity of Cyber Knife on the patients with primary liver cancer at early stage who never accept surgical resection. [Methods] Fifty cases with primary liver cancer at early stage who were not able to accept surgery or reject the surgery underwent Cyber Knife treatment. The diameter of tumor ranged from 0.6 to 5.0 cm,the dose of each irradiation was between 4~12Gy,the number of fractions was 3~8,and the planning target volume(PTV) ranged from 36 to 57 Gy. Continuous irradiation was carried out. [Results]A short-term follow-up of 13 ~51 months was done. Complete response(CR) achieved in 41 cases(82.0%),partial response(PR) in 8 cases(16.0%),no case in stable disease(SD),progression disease(PD) in 1 case(2.0%). The response rate(CR+PR) was 98.0%.The 1-,2- and 3-year survival rates were 100.0%,90.0%,and 76.0% respectively.[Conclusion]Cyber Knife is an effective way to treat the primary liver cancer at early stage with low toxicity.
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