Research Progress on miR-31 in Breast Cancer
WANG Jiang-kun;GUO Bao-liang;The Second Affiliated Hospital of Harbin Medical University;
Breast cancer is the most common malignant tumor among women. In recent years,many studies have revealed that miRNAs participate in the regulation of cell migration,invasion,metastasis and apoptosis of breast cancer through sequence-specific binding to the target genes. Because of involvement in multiple steps of the invasion-metastasis cascade,miR-31 becomes a hot area of research in breast cancer. This article reviews the recent progress on the roles of miR-31 in breast cancer.