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Comparison of Clinical Staging and Surgical/Pathological Staging for Endometrial Carcinoma

ZHAO Xuan-yu;KONG Wei-ming;SHANGRuo-tian;JIAO Si-meng;Beijing Obstetrics and Gynecology Hospital,Capital Medical University;  
[Objective] To examine the differences between clinical staging and surgical/pathological staging for endometrial carcinoma. [Methods] Clinical data of 365 patients with endometrial carcinoma admitted during 2000 to 2010 were retrospectively reviewed. The preoperative diagnosis was made according to FICO(International Federation of Gynecology and Obstetrics) clinical staging criteria(1971),and surgical/pathological staging was made according to FICO surgical/pathological staging criteria(2009). The correlating between clinical,surgical staging with the survival outcomes was analyzed. [Results] Compared to surgical staging,the inconsistence rate for clinical stage Ⅰ patients was 16.15% and that was 82.79% for clinical stage Ⅱ patients. The misdiagnosis rate of preoperative histological grade was 37.19% and 11.25% cases were upgraded to highrisk endometrial carcinoma after surgery. The 5-year overall survival was lower in the clinical stage Ⅰ patients than that in surgical stage Ⅰ patients(χ2=10.32,P=0.001),but there was no difference in 5-year overall survival rate between clinical stage Ⅱ and surgical stage Ⅱ patients.[Conclusion] The inconsistence rate of endometrial cancer between clinical staging and surgical staging is high. It is recommended that preoperative MRI and hysteroscopy should be included in the clinical staging to increase diagnostic accuracy.
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