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Research Progress on Efficacy Evaluation in Maintenance Treatment for Advanced Cancer Patients

LIAN Jie;YANG Yu;Second Affiliated Hospital of Harbin Medical University;  
When the clinical benefit and stable condition are achieved for patients with advanced cancer,the purpose of maintenance treatment is to improve the quantity of life,to delay tumor progression,and to prolong the survival of patients. The terminal point of maintenance treatment is the progression of disease or intolerable adverse effects. It has been generally recognized that to early discover the progression and to adjust second-line therapeutic protocol can prolong the survival. So it is necessary to have indicators for evaluating the efficacy of maintenance treatment and the time of scheduling second-line chemotherapy. In this review,the commonly used evaluation means are discussed,including imaging,tumor markers,molecular detection and clinical features.
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