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The effect of artemisia on IL-2 and IL-6 in IgA nephropathy in rat

MA Yun-xia,LUAN Sen,MA Xing-yi,et al(West China Hospital,Sichuan University,Chengdu 610041,China)  
Objective To observe the effect of artemisia on IL-2 and IL-6 of IgA nephropathy in rat.Methods 50 male SD rats were randomly divided into 5 groups,including control group(C),model group(M),small does artemisia treated group(SDA),high does artemisia treated group(HDA) and ARB treated group(ARB).Interleukin 2 and interleukin 6 were detected with ELISA.Results Artemisia could obviously inhibit IL-2 and IL-6 of IgA nephropathy in rat.Conclusion Artemisia can degrade IL-2 and IL-6 in IgA nephropathy,which may be the mechanism of artemisia on IgA nephropathy.
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