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《Chinese Journal of Animal and Veterinary Sciences》 2004-01
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Study of Iron Absorption and Transport of Iron Amino Acid Chelate by Rats

ZHOU Gui-lian~1,HAN You-wen~2,TENG Bing~3,XU Zi-wei~4,LIU Min-hua~4,XU Ying~4,DENG Bo~4,XU Hai-feng~4(1.Institute of Animal Science,Guang dong Academy of Agricultural Science,Guangzhou 510640,China;2.College of Animal Science,Northeast Agricultural University,Harbin 150030,China;3.Centre of Life Science and Bio-technology,Northeast Agricultural University,Harbin 150030;4.Institute of Animal Science,Zhejiang Academy of Agricultural Science,Hangzhou 310021,China)  
One trail was carried out to research iron absorption,transport and utilization of iron amino acid chelate(Fe-Lys and Fe-Gly)by rats through comparing with the compound of amino acid and FeCl_2 in the same moles of chelate.Rats in normal physiological status were fed two diets,purified diet based on dried skim milk and corn starch and sucrose,and conventional diet based on corn and soybean.The technique of directly perfusing stomach combined with radioactive isotope tracing was used in this study.The results were as follows:①Lysine and glysine could increase absorption,transport and utilization of ferrous in iron-depleted rats.②As compared with FeCl_2 in the same moles of chelate,iron-depleted rats could more easily absorb,transport and utilize iron in iron amino acid chelate,and the same conclusion could be supported by the results of radioactive concentration of different tissues and organs.③Iron of iron amino acid chelate absorbed,transported and utilized by rats,with well iron status,were better than those of FeCl_2.④The results obtained from this study indicated that iron amino acid chelate could be considered as an excellent iron additive.⑤Through investigating dynamic change of radioactive concentration of ~(59)Fe in blood,red cell,serum globin,duodenum,the technique of direatly perfusing stomach combined with radioactive isotope tracing was an appropriate method to study iron absorption,transport and utilization by animals.
【Fund】: 黑龙江省青年基金项目(Q00C016)资助
【CateGory Index】: S852.2
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