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《Chinese Journal of Animal and Veterinary Sciences》 2004-01
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Formation Mechanisim of the Caculus Bovis in the External Artificial Gallbladder

LI Jian-ji,YAN Zhen-gui,LIU Cui-yan,LIU Jun-dong,LI Qiang(College of Animal Science and Technology,Shandong Agricultural University,Taian 271018,China)  
Five healthy cattle were used to cultivate the Calculus Bovis in the external artificial gallbladder(EAG)and were simultaneously performed catheterization of the hepatobiliary ducts for draining the liver bile.During the period of cultivating the Calculus Bovis,the physical and chemical characters of the bile(including the intrahepatic bile and the gallbladder bile and the EAG bile)were analyzed in order to investigate the mechanism of formation of the Calculus Bovis in the EAG.The results showed that as inoculating the E.colic in the bile,the physical and chemical characters changed originally in the intrahepatic bile,the normal bile were changed into the Calculus Bovis-forming bile.While the bile moved from the intrahepatic duct into gallbladder,the quantity of the mucin and E.coli increased,which made the viscosity of bile increasing and the pH value and the content of cholic acid in the bile decreasing.The formation of the Calculus Bovis microgranules were thus accelerated.The viscosity and pH value of the bile in the EAG were decreased,resulting in the Calculus Bovis microgranules to sink and assemble and adhere to the Calculus Bovis' carrier easily,which prevented the Calculus Bovis granules from moving into the duodenum and improved the output of the Calculus Bovis.The more the body weight of cattle,the more the quantity of bile,and then the higher the output of Calculus Bovis.
【Fund】: 山东省教委资助项目(531—32126)
【CateGory Index】: S852.2
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