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《Chinese Journal of Animal and Veterinary Sciences》 2004-01
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The Difference of the Hemagglutinin of H9N2 Chicken Influenza Viruses Isolated in China and Korea

LIU Jin-hua,WU Qing-min,SHI Wei-min,CHEN Fu-yong,GUO Yu-pu,Hiroshi Kida(College of Veterinary Medicine,China Agricultural University,Beijing 100094,China)  
The phylogenetic relationships among the hemagglutinin(HA)genes of China isolates and those of Korea H9N2 viruses from the database were analyzed.The results showed that China H9N2 isolates and Korea isolates fell into a different lineage.Amino acid sequence at the cleavage site of the HA of China H9N2 viruses possessed a -RSSR/G-motif.However,Korea isolates possessed -ASVR/G,-ASYR/G- or ASGR/G-.Amino acids at positions 183,190,and 226 in the receptor-binding sites of Korea isolates had H,E and Q respectively.These contrast with those of China isolates that had N-183,A,T,or V at position at 190,L or Q at position 226.The present results indicate that the molecular characters of hemagglutinin of Korea H9N2 viruses are different from those of China isolates.
【CateGory Index】: S852.65
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