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《Chinese Journal of Animal and Veterinary Sciences》 2004-01
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Experimental Studies on Endotoxin-induced Acute Renal Failure

ZHOU Jian-guo,WU Li-fu(Department of Veterinary Medicine,Guizhou University,Guiyang 550025,China)  
The model group rabbits were given two intravenous injections of E.coli O_(111)B_4 endotoxin with an interval of 24 hours(15 μg·kg~(-1) and 35 μg·kg~(-1) respectively).From the second hour after the 2nd injection,serial urine samples were collected by a bladder fistula at 1 h intervals for six hours.After the collection of the urine samples bleeding was immediately made from heart.Urinary output,plasma and urine level of creatinine and urea nitrogen,serum and urine level of sodium and the osmotic pressure of serum and urine were measured.The excretion of creatinine and urea nitrogen,endogenic creatinine clearance(a reflection of glomerular filtration rate),urinary sodium excretion,renal failure index and fractional excretion of sodium,the ratio of urinary osmotic pressure to serum osmotic pressure,osmotic clearance and free water clearance were calculated on the basis of the above determination.The results showed that urinary output and the excretion of creatinine and urea nitrogen were significantly decreased(P0.05,P0.01,P0.001),urinary sodium,renal failure index and the fractional excretion of sodium were markedly increased(P0.05,P0.01),glomerular filtration rate,urinary osmotic pressure,the ratio of urinary osmotic pressure to serum osmotic pressure and osmotic clearance was significantly declined(P0.05,P0.01,P0.001) as compared with the saline-injected control rabbits,and the free water clearance tended to zero.
【Fund】: 贵州省自然科学基金资助项目[黔基合计字(2001)3035号]
【CateGory Index】: S852.3
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【References】
Chinese Journal Full-text Database 1 Hits
1 WU Li-fu~1, ZHOU Jian-guo~(1,2) (1.Department of Veterinary Medicine, Guizhou University, Guiyang 550025,China; 2.Yunnan Veterinary Service Centre, Kunming 650051, China);Experimental Studies on Pathogenesis of Endotoxin-induced Acute Renal Failure[J];Chinese Journal of Animal and Veterinary Sciences;2005-03
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1 Li Jian chunChen Qiaolin(Jiangsu University Physical Education Department Zhenjian g212001);The Effect of Strenuous Exercise On The Students'Urine Formed Elements[J];Journal of Anhui Sports Science;2002-04
2 LI Hui,WANG Wei,SHANG Li qun, et al. (Deparment of Thoracic Surgery, Navy General Hospital,Beijing 100037,China);Predictive factors of early treatment for open chest injury and seawater immersion[J];Journal of Traumatic Surgery;2002-S1
3 JIANG Fu ting,WANG Yu hong,DUAN Yun you,et al. (General Hospital of Navy,PLA,Beijing 100037,China);Effects of seawater immersion on serum osmotic pressure and electrolyte balance in dogs after open abdominal injury[J];Journal of Traumatic Surgery;2003-05
4 ;Laboratory Diagnosis of Early Renal Lesion[J];;1999-05
5 YUE Xiu ling, SUN Yue hong, WANG Su ping (Department of Clinic Laboratory, Beijing Tiantan Hospital, Capital University of Medical Sciences, Beijing 100050, China);Clinical application of a monoclonal antibody method in determining urine hemoglobin[J];Acta Academiae Medicine Militaris Tertiae;2002-07
6 BAO Zeng-lan (The First People' s Hospital of Nanning,Guangxi Nanning530022,China);The infant severe laxness and the hyperosmolarity[J];Journal of Pediatric Pharmacy;2003-05
7 Chen Zhengxing ; Yao Huiyuan (School of Food Science and Technology, Wuxi University of Light Industry, Wuxi 214026);Ion-exchange Chromatography of Lipopolysacchrides from Plant Origin[J];CHINESE JOURNAL OF ANALYTIEAL CHEMISTRY;2000-03
8 Li Jianqing, Feng Xiaohua, Shuang Shaomin, Jin Weijun, Dong Chuan * (Department of Chemisitry,Shanxi University, Taiyuan 030006);Study on Pharmaco Kinetic of Ofloxacin by Paper Substrate-Room Temperature Phosphorimetry[J];Chinese Journal of Analytieal Chemistry;2001-08
9 Chen Zhengxing*, Yao Huiyuan (School of Food Science and Technology, Southern Yangtze University, Wuxi 214036);Comparison between DEAE-Sephadex and Q Sepharose in Chromatography of Lipopolysaccharide from Plant Origin[J];Chinese Journal of Analytical Chemistry;2003-07
10 LIANG Zhirong CAI Zaoru LI YingchangThe medical laboratory of the first people's hospital of foshan ,Guangdong foshan 528000;Significance Of Urinary Sediment White Blood Cell Detected By Combinational Use Of Methods[J];International Medicine & Health Guidance News;2006-20
【Co-references】
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1 Guo Deyu; Qiao Yiran; Cheng Yishen(Dept of Pathol, Third Military Medical College, Chongqing 630038);An experimental study on lipopolysaccharide-induced renal pathological changes and their mechanisms in rats[J];CHINESE JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOG;1995-03
2 ZHU Fang shi, SI Jian min (Zhejiang University, Sir Run Run Shaw Clinical Medicine Institute, Hangzhou\ 31 0016, China);The Research Survey of Experimental Animal Model about Chronic Atrophic Gastritis[J];Laboratory Animal Science and Administration;2004-01
3 WAN Shao-dong, SUN Lian-jie, HE Yong-cheng, WAN Qi-jun, XU Yi, XU Hui-li (Department of Nephmlogy, Shenzhen Second People's Hospital, Guangdong Shenzhen 518035; Shenzhen Advanced Vocational Technology College, Guangdong Shenzhen 518000);The Establishment of the Rat Model of Schemic Acute Renal Failure[J];Shenzhen Journal of Integrated Traditional Chinese and Western Medicine;2005-04
4 Chen Xiaowen;Yang Huabing;Mai Weimin. et al.(Division of Nephrology, The AffiliatedHospital of Guangdong Medical University, Zhanjiang 524001);A STUDY ON COMBINED TREATMENT WITH ANP AND DOPAMINE IN ACUTE RENAL FAILUREIN RATS[J];CHINESE JOURNAL OF INTERNAL MEDICINE;1995-09
【Secondary References】
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1 HUANG Wei-xin LIU Jun-fu LIU Jian-chi XIE Ming-xin DAI He LIANG Teng-bing LIANG Chao-yue CHEN Hui (Grade 2004,Department of Clinicl Medicine Sciences,Guangxi Medical University,Nanning,Guangxi 530021,China);Complete bilateral ureteral obstruction impacts on the renal function of rabbits[J];Journal of Youjiang Medical College for Nationalities;2008-01
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