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《Chinese Journal of Animal and Veterinary Sciences》 2019-01
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Advances in the Interaction among Gut Phage,Bacteria and Host and Its Impacts on the Animal Host Health

ZHOU Bei;LIN Yan;ZHU Weiyun;National Center for International Research on Animal Gut Nutrition,Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health,Laboratory of Gastrointestinal Microbiology,Nanjing Agricultural University;  
In recent years,the research on the function of gut virome has attracted increasing attention.As a main component of the gut virome,intestinal phage has become a research hotspot.Numerous studies have shown that the diversity and abundance of gut phage not only directly affect the gut microbiota,but also have close correlation with host function,playing an important role in modulation of host health.In this review,we summarize current research progress in the interaction between gut phage and bacteria,the interaction between phage and animal host,and the relationship between gut phage and diseases such as inflammatory bowel disease and metabolic disease.This review will provide a theoretical basis and new perspective for further study on the effect of gut phage on animal health.
【Fund】: 国家自然科学基金重点项目(31430082)
【CateGory Index】: S852.6
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