Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Medical Journal of National Defending Forces in Southwest China》 1991-01
Add to Favorite Get Latest Update

The mechanisms of the changes in endocrine function of pancreatic islet B-cells after pancreatic duct obstruction

Li Zhan-jing, et al. General Hospital of Chengdu Command Unit, PLA  
Pancre atic duct obstruction (PDO) was performed with an a-cyanoacrylate glue in 8 healthy beagles. Pancreatic biopsies were taken in 5 of the animals. Biop sies were studied on histology and ultrastructure in order to reveal the mechanisms in the decrement of the endocrine function of pancreatic islet B-cells. The exocriae tissue was almost replaced by fibrodid with scattered inflammatory cells. Pancreatic islets were edematous and fibrosis. B-cells were damaged in different degrees. Our results show that the hypoinsulinisms are mainly due to the decrease of the number of the B-cells, the structural damages and metabolic disturbance of the residual B-cells, as well as the microenvironmen tdisorder in the pacreas islets.
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved