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《Medical Journal of National Defending Forces in Southwest China》 2014-01
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Value of inflammation and nutrition indexes in the prediction of clinical turnover in patients with lower respiratory infection in RICU

Huang Lei;Chen Yi;He Yeying;Department of Trophology,General Hospital of Chengdu Military Command;Department of Respiratory Diseases,General Hospital of Chengdu Military Command;  
Objective To discuss the value of inflammation and nutrition indexes in the prediction of clinical turnover in patients with lower respiratory infection in RICU. Methods The receiver operating characteristic curve( ROC curve) was used to calculate the area under the curve( AUC) in order to analyze the value of the indexes below in the prediction of death within 25 days after the admission and the application of mechanical ventilation. The indexes included PCT,Hs-CRP,Alb,PA,Bun,Cr,TC,TG,HDLC,LDL-C,Hb,and LY of the 143 patients with lower respiratory infection at the time of admission in RICU. The correlation between the inflammation and the nutritive indexes was analyzed. Results Based on ROC curve analysis of death within 25 d,the AUC of PCT was the highest( 0. 70),and the AUCs of other indexes were all larger than 0. 50. There were significant differences in LY,PCT,Alb,and PA between the death within 25 days group and non-death group( P 0. 05). In the ROC curve of the prediction of mechanical ventilation application,the AUC of LY was the highest,and the AUCs of other indexes were all larger than 0. 50 except PA and Cr. There were significant differences in the LY,PCT,Alb,and PA between the groups receiving and not receiving the mechanical ventilation( P 0. 05). There was a negative correlation between the level of PCT and Hb,PA,Alb,TC,HDL-C,and LDL-C( P 0. 05 or P 0. 01) and a positive correlation between the level of Bun and Cr( P 0. 01). There was a negative correlation between the level of Hs-CRP and PA and Alb( P 0. 01). Conclusion PCT and LY have a great independent value in the prediction of the recent death and the application of mechanical ventilation in patients with severe lower respiratory infection,and the PCT level is closely related to the nutriture.
【CateGory Index】: R56
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