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《Medical Journal of National Defending Forces in Southwest China》 2016-01
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Treatment of recurrent Aphthous ulcers by Ouboning combined with semiconductor laser

Wang Zhenchuan;Sun Weibin;Ding Yan;Xie Le;Xü Ke;Department of Periodontics, Dental Hospital of Medical College of Nanjing University;Department of Endodontics, Dental Hospital of Medical College of Nanjing University;Department of Dentofacial Surgery, Dental Hospital of Medical College of Nanjing University;  
Objective To discuss the efficacy and safety of Ouboning combined with semiconductor laser in the treatment of recurrent aphthous ulcers. Methods 251 patients with recurrent aphthous ulcer receiving the treatment between December 2013 and December 2014 were selected and randomly divided into treatment group(126 cases) and control group(125 cases). The control group was given semiconductor laser therapy, and the treatment group received Ouboning combined with semiconductor laser treatment. The course of treatment for both groups was one week. Results The full recovery rate and the total effective rate of the treatment group were higher than those of the control group(P 0.05). After the treatment, the ulcer diameter and pain scores of the two groups were significantly smaller and lower than those before the treatment, and the decreasing range of the treatment group was larger than that of the control group(P 0.05). During the treatment, the degrees of adverse reactions like dizziness, numb tongue, mouth irritation,nausea, and vomiting in the two groups were mild. These adverse reactions were relieved after symptomatic treatment, and there was no significant difference between the two groups(P 0.05). Conclusion The treatment of recurrent aphthous ulcers by Ouboning combined with semiconductor laser can promote the healing of the ulcers, relieve the pain, and improve the therapeutic effects. It has good security and should be widely applied.
【Fund】: 国家自然科学基金资助课题(51472115)
【CateGory Index】: R781.59
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