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《Medical Journal of National Defending Forces in Southwest China》 2016-01
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Changes of plasma BNP, ANP, and CKMB levels in AMI patients before and after treatment and its clinical significance

Wu Wenfeng;No.4 Endemic Area of Cadres' Ward, General Hospital of Chengdu Military Command;  
Objective To explore the characteristics of plasma brain natriuretic peptide(BNP), atrial natriuretic peptide(ANP),and creatine kinase(CKMB) level changes in patients with acute myocardial infarction(AMI) and the clinical significance. Methods110 cases of AMI patients receiving treatment in the hospital between January 2013 and December 2014 were selected as AMI group,and other 110 persons taking health examination at the same period were chosen as control group. The plasma BNP, CKMB, and ANP levels in both groups were detected in order to analyze the changes before and after the treatment. Results Before the treatment, the BNP, ANP, and CKMB levels in AMI group were all higher than those in the control group(P 0.01). After the treatment, the levels of the three indexes above in AMI group significantly decreased but still higher than those in the control group(both P 0.01). Before the treatment, the BNP, CKMB, and ANP levels of the patients with anterior myocardial infarction were significantly higher than those of the patients with inferior wall myocardial infarction(P 0.05). Within 30 days after the treatment, the levels of the three indexes in the group with the occurrence of cardiovascular events(recurrent myocardial infarction and heart failure) were all higher than those in the group without the occurrence(P 0.05). Conclusion The detection of plasma BNP, CKMB, and ANP levels has important significance for the diagnosis and disease surveillance of AMI patients.
【CateGory Index】: R542.22
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