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《Medical Journal of National Defending Forces in Southwest China》 2016-04
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Postoperative curative effects of gemcitabine combined with XELOX chemotherapy on patients with colorectal cancer

Shang Shuping;Dang Yong;Department of Oncology, Central Hospital of Tongchuan Mining Bureau,Tongchuan;Imaging Center, Central Hospital of Tongchuan Mining Bureau;  
Objective To investigate the postoperative clinical curative effects of gemcitabine combined with XELOX chemotherapy on patients with colorectal cancer and the influence on their quality of life. Methods 80 patients receiving the operation on colorectal cancer were randomly and averagely divided into two groups. Observation group was given the treatment with gemcitabine combined with XELOX chemotherapy, while control group was given XELOX chemotherapy. Fourteen days were a course of treatment, and the treatment course was 8 weeks. Observation was made in the clinical curative effects and patients' life quality after the treatment between the two groups. Results The remission rates and the disease control rates of the observation group were superior to those of the control group(P 0.05). After the treatment, the scores of the life quality in the aspects of abdominal distension, hair loss, the anus exhaust, the overall quality of life, role function, emotional function, cognitive function, social function,fatigue, nausea and vomiting, insomnia, and economic difficulties in the observation group were better than those in the control group(P 0.05). Conclusion The combination of gemcitabine and XELOX chemotherapy has certain postoperative clinical curative effects on patients with colorectal cancer and has less adverse reactions, which can improve the patients' life quality and is worthy of clinical application.
【CateGory Index】: R735.34
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