Study on value of ECG in screening neonatal myocardial injury and its correlation with intrauterine hypoxia
Zuo Jin;Gao Yuan;Shan Zhaoliang;Xu Hui;Lu Yuanyuan;Yang Xiaobin;Health Examination Center for Aviation and Maritime Crew, Navy General Hospital of PLA;Department of Cardiology, General Hospital of PLA;
Objective To explore the value of ECG in the clinical screening of neonatal myocardial injury and its correlation with intrauterine hypoxia. Methods The clinical data of 25 neonates with intrauterine hypoxia and 58 neonates without intrauterine hypoxia who were born in our hospital in the same period were retrospectively analyzed and divided into an observed group and a healthy group. The neonates in the two groups were examined by myocardial enzymes and ECG. The abnormal rates of myocardial enzymes and ECG were compared between the two groups. Results(1)The levels of creatine kinase-MB(CK-MB) and creatine kinase(CK) in the observed group within 24 h after birth were significantly higher than those in the healthy group( P 0.05); the abnormal rates of CK-MB and CK in the observed group(92.0%, 80.0%) were much higher than those in the healthy group(17.2%, 13.8%)(P 0.05).(2)No atrioventricular block was found by ECG in the two groups. There were 15 abnormal cases(60.0%) in the observed group, which were significantly more than those(six cases, 10.3%) in the healthy group( P 0.05).(3)The four neonates in the healthy group who underwent echocardiography were normal; among the eight neonates in the observed group who underwent echocardiography, there were three cases of tricuspid regurgitation and five cases of decreased right ventricular ejection fraction.Conclusion Intrauterine hypoxia is closely related to myocardial injury in neonates. After birth, neonates should be examined by ECG in time to improve the early detection rate of myocardial injury and provide basis for the smooth development of the follow-up treatment.
【CateGory Index】： R722.1;R540.41