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《Medical Journal of National Defending Forces in Southwest China》 2016-09
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Analysis of PCT expression difference in DM patients of different severity

Wang Lu;Xiong Jie;Qu Yuanqing;Liu Chenxia;Xiong Hongyan;Department of Epidemiology,College of Preventive Medicine,Third Military Medical University;Department of Laboratory,General Hospital of Chengdu Military Command;  
Objective To explore the expression difference of procalcitonin(PCT) among patients with diabetes mellitus(DM) of different severity.Methods A total of 521 DM patients were selected to evaluate the severity by APACHEII scores,Um Alb and other indicators,detect the PCT levels,analyze the difference of PCT,IL-6,TNF-α and INF-γ among groups at different DM severity,and further analyze the correlation between the severity and PCT levels.Results The PCT,IL-6 and TNF-α in DM patients increased with the deterioration of DM severity(P 0.05),but INF-γ dropped(P 0.05).In the group with chronic complications,the levels of PCT were positively related to Um Alb levels(r = 0.705; P 0.01),while in the group with acute complications,the levels of PCT were positively related to APACHEII scores(r = 0.874; P 0.01).Conclusion For DM patients,the levels of PCT are closely related to the severity,thus it can be used as one of the indicators for judging the severity of DM and may have significant value in differential diagnosis of DM severity.
【CateGory Index】: R587.1
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