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《Medical Journal of National Defending Forces in Southwest China》 2016-09
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Comparison of effects of radical radiotherapy and postoperative radiotherapy on treatment of esophagus cancer and quality of life in senile patients

Qin Yinzhong;Department of Radiotherapy,Central Hospital of Tongchuan Mining Administration of Shaanxi Coal and Chemical Industry;  
Objective To compare the effects of radical radiotherapy and postoperative radiotherapy on the treatment of esophagus cancer and quality of life in senile patients.Methods The clinical data of a total of 87 senile patients with esophagus cancer admitted to our hospital from August 2008 to August 2012 were selected for retrospective analysis and divided into a definitive radiotherapy group(n=45) and a postoperative radiotherapy group(n=42) according to the time of radiotherapy.The clinical effects,incidence of adverse reactions,and quality of life and survival rate in the two groups were compared.Results The overall response rate in the definitive radiotherapy group was 82.22% and 88.10% in the postoperative radiotherapy group.There was no statistical difference between the two groups(P 0.05).The incidence of adverse reactions after the treatment in the two groups also had no statistical difference(P 0.05).Six months after the treatment,the physical functioning and overall condition scores in the definitive radiotherapy group were better than those in the postoperative radiotherapy group; and the incidence of such symptoms as regurgitation,anorexia and cough in the definitive radiotherapy group was significantly lower than that in the postoperative radiotherapy group(P 0.05).There was no significant difference of the survival rate one,two and three years after the treatment between the two groups(P 0.05).Conclusion The clinical effects of definitive radiotherapy and postoperative radiotherapy on the treatment of esophageal cancer in senile patients are equivalent.However,definitive radiotherapy may ensure better quality of life and is worth of clinical popularization and application.
【CateGory Index】: R735.1;R730.55
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