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《Medical Journal of National Defending Forces in Southwest China》 2016-09
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Effects of nifedipine on vasospasm in patients undergoing trans-ulnar artery approach PCI

Yang Hong;Liu Quanwei;Li Xueyun;Department of Cardiovascular Internal Medicine,the Second People's Hospital of Meishan City;Department of Cardiology,the Second People's Hospital of Neijiang City;Department of Cardiology,the Second People's Hospital of Meishan City;  
Objective To explore the effects of nifedipine on the risk of ulnar artery spasm during arterial puncture and interventional therapy in patients undergoing trans-ulner artery approach percutaneous coronary intervention(PCI).Methods A total of 112 patients with cardiovascular diseases treated with trans-ulner artery approach PCI were divided into groups A and B(n =56,respectively).Group B was directly treated with trans-ulner artery approach PCI while group A with sub-lingual nifedipine before operation,then trans-ulner artery approach PCI.The changes in the inner diameters of ulnar arteries in the two groups before taking medicine(T0),5min(T1) after taking medicine,20min(T2) after taking medicine were compared.The success rate of one-time puncture,puncture time and incidence of ulnar arterial spasm during arterial puncture and interventional therapy in the two groups were recorded.Results(1)The ulnar artery diameter in group A increased gradually after sub-lingual nifedipine; there was significant difference between the diameters at T2 and T0; the diameters in group A were greater than those in group B at the same time(P 0.05); the ulnar artery diameters in group B has no significant difference(P 0.05).(2)The success rate of one-time puncture in group A(85.71%) was significantly higher than that in group B(66.07%)(P 0.05); and the mean time of puncture in group B was significantly longer than that in group A(P 0.05).(3)The incidence rates of ulnar arterial spasm during ulnar arterial puncture and interventional therapy in group A(3.57% and 5.36%) were significantly lower than those in group B(17.86% and 21.43%)(P 0.05).Conclusion Sub-lingual nifedipine before trans-ulner artery approach PCI can effectively expand blood vessels and reduce the risk of ulnar arterial spasm during puncture and operation,and improve the safety of operation.
【CateGory Index】: R541
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