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《Medical Journal of National Defending Forces in Southwest China》 2016-09
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Effects of acupoint application of TCM on AECOPD and levels of inflammatory factors

Qu Lei;Zhou Liangqiong;Gong Chuanming;Zhang Tao;Li Xiang;Hu Haitao;Department of Respiratory Medicine,Hospital 161 of PLA;Department of Laboratory,Xinqiao Hospital,Third Military Medical University;  
Objective To explore the effects of acupoint application of TCM on acute exacerbation of chronic obstructive pulmonary disease(AECOPD) and levels of inflammatory factors.Methods A total of 128 AECOPD patients were selected and randomly divided into a TCM group(n=66) and a control group(n=62).The control group was treated with anti-inflammation,relieving asthma,reducing phlegm,oxygen inhalation and other complex treatment; on this basis,the TCM group was additionally treated with acupoint application of TCM.The COPD symptom scores and the levels of IL-6,TNF-α and CRP of patients in the two groups were detected three days,one week and two weeks before and after the treatment.The effects in the two groups were compared.Results One week after the treatment,the overall response rate(ORR)(87.8%) in the TCM group was significantly higher than that in the control group(64.51%)(P 0.01); two weeks after the treatment,there was no significant difference in the ORR between the TCM group(96.97%) and the control group(96.77%)(P 0.05).The levels of IL-6,TNF-α and CRP and symptom scores in the two groups after the treatment decreased gradually,but those in the TCM group decreased more greatly than those in the control group(P 0.05).Conclusion Acupoint application of TCM can help lower the levels of CRP,IL-6 and TNF-α of AECOPD patients and improve clinical effects.
【CateGory Index】: R563.9
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