Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Southwest China Journal of Agricultural Sciences》 2008-01
Add to Favorite Get Latest Update

Study on the immunopathology of piglets infected with PRRSV and PRRSV/PCV2

WANG Tian-hu,LOU Zhong-zi,LIU Si-dang*(College of Animal Science and Veterinary Technology,Shandong Agricultural University,Shandong Tai'an 271018,China)  
40-day-old piglets were infected by PRRSVand PRRSV/PCV2 to establish a pathological model.It was used in order to compare the pathological changes of immune organs and peripheral blood lymphocytes which were induced by the two kinds of infection models.The result indicates that both PRRSV and PRRSV/PCV2 infection could cause augment of immune organs index.The most of the immune organ indexes of co-infection were higher than mono-infection group.Pathohistological survey indicates that it was acute exudation and chronic granulomatous inflammation not lymphadenosis that induced the augment of immune organ index.Fortonsil,spleen and the main peripheral lymphoid nodes of the test piglets,dynamic pathohistological survey indicates that monoinfection caused by PRRSV could induces acute inflammation of immune organs,the inflammation was characterized by degeneration and necrosis of lymphocyte and macrophage and could induce immunosuppression.The co-infection by PRRSV/PCV2 not only worsens the lesion but also induces lymphatic folliculus deletion in spleen and granulomatous inflammation of lymphoid nodes.Apoptosis of cells in lymph,lung,spleen and liver were detected by electron microscope and terminal deoxynucleotidyl transferase UIP nick end labeling(TUNEL) on the piglets.The results showed PRRSV and PRRSV/PCV2 infection could induce incoordinate apoptosis of cells in above organs.And the lymphocyte apoptosis were seriously in spleen,lymph and lung.These organs appeared apoptosis in earlier time and necrosis of lymphocytes in later time,being seriouser in the piglets infected with PRRSV/PCV2.So the apoptosis in earlier time and necrosis of lymphocytes in later time was one of the cause of immunorepression on the piglets.
【CateGory Index】: S858.28
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 2 Hits
1 SUN Yan-yong1,LIU Zhi-jun1,WANG Ze2,LIAN Hai3,GAO Feng1,XIA Zhi-ping1,31.College of Animal Science and Veterinary Medicine,Jilin Univerity,Changchun 130062,China; 2.College of Animal Science and Technology,Jilin Agricultural University,Changchun 130118,China;3.Institue of Veterinary Medicine,Academy of Military Medical Sciences of PLA,Changchun 130062,China;Diagnosis of Co-Infection of Porcine Reproductive and Respiratory Syndrome and Porcine Circovirus Type 2[J];Journal of Jilin Agricultural University;2009-06
2 ZHANG De-yu,HE Yi-min,QIN Hong-yang,ZHANG Xiang-feng,HE Ran-ya,CAO Zong-xi,ZHANG Gui-hong(College of Veterinary Medicine,South China Agricultural University,Guangzhou 510642,China);Cloning and Sequencing of Complete Genome of Porcine Circovirus Type 2(PCV2) Guangdong Strains[J];Journal of South China Agricultural University;2010-01
【Citations】
Chinese Journal Full-text Database 1 Hits
1 ZHU Jun-Li~(1), YU Xu-Ping~(1), SHI Han~(2), WU Hai-bo~(1), JIN Jun-jie~(1), HE Shi-cheng~(1) (1. College of Animal Science, Zhejiang University, Hangzhou 310029, China; 2. College of Life Science, Northeast Agricultural University, Harbin 150030, China);Establishment of the multiplex PCR for detection of porcine circovirus[J];Chinese Journal of Veterinary Science and Technology;2004-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 WANG Xian-wen et al(College ofAnimal Science,South China Agricultural University,Guangzhou,Guangdong 510642);Expression and Purification of ORF2 Gene Fragment of Porcine Circovirus Type 2 in E. coli[J];Journal of Anhui Agricultural Sciences;2007-23
2 ZHU Wen-hao~1,ZHANG Yi-fang~1,XU Guo-dong~2 (1.College of Animal Science and Technology,Yunnan Agricultural University,Kunming,Yunnan,650201,China; 2.Institute of Veterinary Hygiene Supervision,Xuanwei,Yunnan,655400,China);Advance in Diagnostic Technology of Porcine circovirus[J];Progress in Veterinary Medicine;2006-12
3 ZHAO Bing-wu1,3,YU Hai-xia2,HAO Yong-qing1,JIANG Zhi-yong3,SONG Chang-xu3(1.College of Animal Science and Veterinary Science,Inner Mongolian Agriculture University,Hohhot,Inner Mongolian,010018,China;2.Gaoming Entry-Exit Inspection and Quarantine Bureau,Gaoming,Guangdong,528500,China;3.Institute of Veterinary Medicine,Guangdong Academy of Agricultural Sciences,Guangzhou,Guangdong,510640,China);A New Approach for Porcine circovirus Type 2 Isolation and the Full Length Genome Analysis of Guangdong Isolate[J];Progress in Veterinary Medicine;2008-04
4 GU ji-xiu1,2,LIU Yan-hong2,YIN Shuang-hui2,SONG Bing1,LIU Xiang-tao2(1.College of Veterinary Medicine,Gansu Agricultural University,Lanzhou,Gansu,730070,China;2.Institute of Animal Veterinary Medicine,CAAS,Lanzhou,Gansu,730046,China);Cloning and Sequence Analysis of ORF2 Gene of Two PCV-2 Strains[J];Progress in Veterinary Medicine;2008-05
5 LIU Yan-ling1,JIANG Zhi-yong1,HUANG Zhong1,LIN Zhi-xiong2,SONG Chang-xu1(1.Veterinary Medicine Institute,Agricultural Sciences Academy of Guangdong,Guangzhou,Guangdong,510640,China;2.Guangzhou Entry-Exit Inspection and Quarantine Bureau,Guangzhou,Guangdong,510623,China);Epidemiological Investigation of Porcine circovirus Type 2 by PCR in Guangdong Province[J];Progress in Veterinary Medicine;2008-09
6 SUN Yan-ming,ZHAO De-ming(College of Veterinary Medicine,China Agricultural University,Beijing 100094,China);The Progress of Molecular Biology in Porcine Circovirus[J];China Animal Husbandry & Veterinary Medicine;2006-07
7 YANG Xiao-yan,ZHENG Xin-tian,DAI Ai-ling,LI Xiao-hua;Cloning and Sequence Analysis of Full Genome of Fujian Strain Porcine Circovirus Type 2[J];Journal of Longyan University;2007-06
8 LOU Zhong-zi,WANG Tian-hu,DONG Li-min,LIU Si-dang(College of Animal Science and Veterinary Medicine,Shandong Agricultural University,Taian 271018,China);ISOLATION AND IDENTIFICATION OF PCV2SDT AND PHYLOGENETIC ANALYSIS[J];Journal of Shandong Agricultural University(Natural Science Edition);2007-04
9 YANG Zeng-qi1,TIAN Xiao-yan1,ZHANG Yong1,ZHU Wei-guo1,WANG Xu-rong1,XIE Jun-liang1,YANG Yong-ning2,ZHANG Jinjun3(1 College of Animal Science and Technology,Northwest A & F University,Yangling,Shaanxi 712100,China;2 Shaanxi Animal Husbandry and Veterinary Station,Xi'an,Shaanxi 710016,China;3 Yuyang Inspection and Quarantine Bureau,Yulin,Shaanxi 719000,China);Isolation and identification of PCV2 in Shaanxi[J];Journal of Northwest A & F University(Natural Science Edition);2007-07
10 LOU Zhong-zi1,WANG Tian-hu1,YANG Xian-yong2,LIU Si-dang1*(1.College of Animal Science and Veterinary Medicine,Shandong Agricultural University,Shandong Tai'an 271018,China;2.Central Hospital of Tai'an,Shandong Tai'an 271000,China);Study on hematopathology of piglets infected with porcine reproductive and respiratory syndrome virus(ATCC VR-2332) and porcine circovirus type 2[J];Southwest China Journal of Agricultural Sciences;2008-04
China Proceedings of conference Full-text Database 1 Hits
1 Wang Xian-wen~1 Wang Yan~2 Liu Xing-you~1 Yang Chong-xin~1 (1.Henan Sicence and technology institute Xinxiang 453003, 2.veterniary school of Zhengzhou Zhengzhou 450002);Cloning and Sequence Analysis of Porcine Circovirus type 2 Strains from Henan Province[A];[C];2008
【Co-references】
Chinese Journal Full-text Database 8 Hits
1 HE Yi-min,LUO Yu-jun,PAN Quan-hui,WU Cui-hua,CAO Zong-xi,KONG Liu-wu,LI Shao-fang,ZHANG Gui-hong(College of Veterinary Medicine,South China Agricultural University,Guangzhou,Guangdong,510624,China);Cloning and Sequence Analysis of ORF2 Gene of Porcine circovirus Type 2[J];Progress in Veterinary Medicine;2007-11
2 HE Yi-min,KONG Liu-wu,LUO Yu-jun,PAN Quan-hui,CAO Zong-xi,ZHANG Gui-hong(College of Veterinary Medicine,South China Agricultural University,Guangzhou 510624,China);Molecular Cloning,Sequencing and Analysis of the Complete Genome of two Porcine Circovirus Type 2 Isolates[J];Journal of South China Agricultural University;2008-03
3 LIU Yan, QIAN Ai-dong~() (College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin 130118 , China);Establishing Method of RT-PCR Detecting H_5,H_9 Subtypes of Avian Influenza Virus[J];Journal of Jilin Agricultural University;2004-01
4 WANG Chun-feng~1,YU Shou-ping~1,YANG Shu-bao~1,LI Yu~2(1.College of Animal Science and Technology,Jilin Agricultural University,Changchun 130118,China;2.Institute of Mycology,Jilin Agricultural University,Changchun 130118,China);Cloning and Sequencing of Full Vp4 Gene of Group A Porcine Rotavirus[J];Journal of Jilin Agricultural University;2005-05
5 Guo Baoqing(Harbin Veterinary Research Institute,the Chinese Academy of Agricultural Sciences);Isolation and Identification of Porcine Reproductory and Respiratory Syndrome(PRRS) Virus from aborted fetuses suspected of PRRS[J];;1996-02
6 WEN Yong-jun WU Guo-jun CAI Xue-hui LIU Yong-gang WANG Hong-feng JIANG Cheng-gang YIN Xun-nan (Division of Swine Infectious Diseases,National Key Laboratory of Veterinary Biotechnology,Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences,Harbin 150001,China);Pathogenicity of porcine reproductive and respiratory syndrome virus and porcine circovirus type 2 coinfection in piglets[J];Chinese Journal of Preventive Veterinary Medicine;2007-05
7 Chen Buowen Sun Yingjie~* Luo Changbao Sun Yanfeng~* Pan Fengcheng~* Lin zhixong Su Yongsheng~* Li Shugen Tong Kunzhou (Guangzhou Animal & Plant Quarantine Bureau,510010 ~*Dalian Animal & Plant Quarant Bureau);Isolation and Identification of Porcine Reproductive. and Respiratory Syndrome (PRRS) virus: A Preliminary Report[J];Chinese Journal of Veterinary Medicine;1996-05
8 WANG Zhong- tian,YANG Han- chun,GUO Xin (Key L aboratory of Preventive Veterinary Medicine,Ministry of Agriculture, China Agricultural University,Beijing10 0 0 94 ,China);Epidemiological investigation on infection of PCV2 in intensive swine farms[J];Chinese Journal of Veterinary Medicine;2002-10
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Cao Shengbo Chen Huanchun Xiao Shaobo He Qigai Xu Yindi Liu Junfa (Huazhong Agricultural University, Wuhan 430070,China);The Establishment And Application of PCR to Diagnosis Porcine Circovirus Type 2[J];Journal of Huazhong Agricultural;2001-01
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved