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《Journal of Southwest China Normal University(Natural Science Edition)》 2006-01
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Gold Nanoparticles Modified Biosensor for Detection of α-Fetoprotein(AFP)

ZHU Qiang,YUAN Ruo,CHAI Ya-qin,LI Xue-lian,WANG NaSchool of Chemistry and Chemical Engineering,Southwest University,Chongqing 400715,China  
Gold nanoparticles were electrodeposited on the surface of glass carbon(GC) electrode,then anti-AFP was absorbed by gold nanoparticles to prepare a biosensor.The effect of electrodeposition time and absorption time on the electrochemical behavior of biosensor was studied.Other experimental conditions such as pH and temperature were studied too.The current response of the biosensor is in linear relationship with concentration of AFP in the range of 2 ng/mL~60 ng/mL.This approach has some advantage such as simple,a short response time and a satisfied detection range.
【Fund】: 国家自然科学基金资助项目(29705001);; 教育部优秀青年教师资助计划项目(200240);; 重庆市自然科学基金资助项目(20027477)
【CateGory Index】: TP212
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