Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Southwest China Normal University(Natural Science Edition)》 2006-01
Add to Favorite Get Latest Update

The Different Sensitivity to Iodide Inducing Thyroid Cells Apoptasis of Normal and AITD Patients

HU Huai-dong,ZENG Xiao-hua,LIU Dong-fang,WANG Yu-junDepartment of Endocrinology,The Second Affiliated Hospital of Chongqing University of Medical Science,Chongqing 400010,China  
Objective To explore the role of the excessive iodide on inducing apoptosis in thyroid cells from normal subjects and AITD patients.Methods primary thyroid cells were cultured with different concentration iodide, apoptosis rate of TECs was determined by flow cytometry techique,in the meantime Fas,Fasl,p53 level were determined by histochemistry.Results Thyroid cell treated with iodide excess underwent the morphological changes and apoptosis.There is a gradually increased apoptosis rate and Fas/Fasl protein expression accompanying with iodide concentration rising.The apoptosis rate and protein of GD and HT group were higher than control group.Conclusion: there is more sensitivity of apoptosis to iodide in AITD patients.
【Fund】: 重庆市卫生局青年人才基金资助项目(2001115)
【CateGory Index】: R581
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 ZHANG Danying,LEI Yanxia,ZHAO Junjie,TAN Wuhong,et al.Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education,Xi'an Jiaotong University,Xi'an 710061,China;The change of certain biochemical indexes and apotosis protein (Fas/Fasl) expression in rat liver of selenium and iodine deficiency[J];Journal of Hygiene Research;2008-06
Chinese Journal Full-text Database 4 Hits
1 YANG Fan *,TENG Weiping,SHAN Zhongyan,et al.Department of Endocrinology, the First Affiliated Hospital of China Medical University,Shenyang 110001;A comparative epidemiologic survey of hyperthyroidism in areas with different iodine intake[J];Chinese Journal of Endocrinology and Metabolism;2001-04
2 LIU Jian-xia, QIN Lei, ZUO Jian-ling, TIAN Li-ping, QIAN Hai-xin. Department of General Surgery, The First Hospital Affiliated to Suzhou University, Suzhou 215006;Role of Fas/FasL mediated apoptosis in the pathogenesis of Hashimoto′s thyroiditis[J];Chinese Journal of Endocrinology and Metabolism;2003-02
3 LIU Dong-fang, DENG Hua-cong, XU Gai-ping, XIONG Bo, HOU Ping. Department of Endocrinology, The First Hospital Affiliated to Chongqing Medical University, Chongqing 400016;Long-term primary culture of human thyroid cells[J];Chinese Journal of Endocrinology and Metabolism;2005-02
4 LIU Dongfang,et al (Department of Endocrinology,College of Clinical Medicine,Chongqing Medical University);Induction of apoptosis in thyroid cells by iodide excess and its mechanism[J];Journal of Chongqing Medical University;2004-04
Chinese Journal Full-text Database 10 Hits
1 ZENG Xiao-hua,LIU Chang-an,WANG Ji-jian,YIN Guo-bing(Department of General Surgery,The Second Hospital of Chongqing University of Medical Sciences,Chongqing 400010,China);Expression and influencing factors of CD54 in Hashimotos thyroiditis[J];Acta Academiae Medicinae Militaris Tertiae;2006-17
2 Wei Wenhua;Dietary investigation and nursing countermeasure analysis for Island hyperthyroidism patients[J];Journal of Nurses Training;2010-05
3 HU Ying-ying,JIANG Ning-yi,LIU Xiong-ying,ZHANG Hong,WU Yan-feng.Department of Nuclear Medicine,Cancer Center,Sun Yat-Sen University,Guangzhou 510060,China;Committing E14 mouse embryonic stem cells to differentiate into thyrocyte-like cells in three-diamension collagen gel.[J];Guangdong Medical Journal;2009-03
4 LI Yang,LIU Xin (Third Military Medical University,Zhongqing 400038,China);Iodine and Human Health[J];Trace Elements Science;2003-10
5 QIN Junfa1,LOU Manteng2,LI Zengxi2,XIAO Yixin2(1.Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai 201800,China; 2.Trace Elements Science Association of Guangdong Province,Guangzhou 510070,China);Iodine-induced Thyroid Disease:A Public Health Problem Can Not Be Ignored[J];Guangdong Trace Elements Science;2010-05
6 ZHANG Qing-lan ZHOU Yong-lin WANG Pei-hua SHANG Li CHEN Zhi-gao CHEN Yue-e WU Ming ZHOU Ming-hao CHEN Zu-pei ZHAO Jin-kou(1.Department of Chronic Non-communicable Diseases,Jiangsu Provincial Center for Disease Control and Prevention,Jiangsu,Nanjing 210009,China;2.Xuzhou Center for Disease Control and Prevention,Jiangsu,Xuzhou 221003,China;3.Tianjin Medical University,Tianjin 300070,China);Subclinical Hypothyroidism in a Population with Long Term Environmental Excessive Iodine Intake[J];Journal of Environmental & Occupational Medicine;2008-04
7 PENG Wen,WANG Xiao-dong,DUAN Yu,FENG Yu,FENG Shang-yong,TANG Wei,MAO Xiao-dong,LIU Chao (Department of Endocrinology,the First Affiliated Hospital of NJMU,Nanjing 210029,China);Epidemiologic study of thyroid dysfunction in community population of Nanjing[J];Acta Universitatis Medicinalis Nanjing(Natural Science);2010-04
8 CHEN Yu,LIU Dong-fang1*,YE Guo(Internal Medicine Department of Chongqing Cancer Institute,Chongqing 400030;1Department of Endocrinology,the Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China);The determination of apoptosis and expression of Fas /FasL in thyroid cells of AITD[J];Acta Universitatis Medicinalis Nanjing(Natural Science);2010-05
9 XIAO Bang-zhong1,LIAO Wen-fang1,LI Xin-shu1,LUO Xin-jian1,WU Cheng-guo1,XU Shi-bin2,ZHANG Ren-ping3,LIAO Yun-zhen,CHEN Ya-ling1,XIE Jun1 (1. Chongqing Center for Disease Control and Prevention,Chongqing 400042; 2. Chongqing Yongchuan Center for Disease Control and Prevention,Chongqing 402160; 3. Chongqing Fuling Center for Disease Control and Prevention,Chongqing 408000,China);Analysis on the Influence of Universal Salt Iodization to Hyperthyroidism[J];Journal of Tropical Medicine;2010-05
10 TIE Li-li,ZHANG Ya-ping,WANG Ying-mei,et al.(Department of Endocrinology,Xijing Hospital,Fourth Military Medical University,710032,China);Effect of excess iodine on thyroid function and Trail expression in rats[J];Medical Journal of National Defending Forces in Northwest China;2007-05
Chinese Journal Full-text Database 10 Hits
1 Hua Chuan, Chen Ruquan Nanjing University of Traditional Chinese Medicine, Nanjing 210029 Hubei College of Traditional Chinese Medicine, Wuhan 430061;Effects of Qijian Xiaoying Decoction on TNF, IL-6 of Autoimmune Thyroiditis in Mice[J];Journal of Hubei College of Traditional Chinese Medicine;2004-01
2 Gu Zhifeng~1,Yu Jiangyi~2,Cao Xiaolei~3(1.Incretion Dept.,Affiliated Hospital of Nantong University,Nantong 226001,Jiangsu,China;2.Incretion Dept.,Jiangshu Chinese Medicine Hospital,Nanjing 210009,Jiangsu,China;3.Basic Medical College of Nantong Vniuersity,Nantong 226001,Jiangsu,China);Effect of Wenshenfang on Apoptosisof Expermental Autoimmune Thyroiditis[J];Liaoning Journal of Traditional Chinese Medicine;2006-08
3 XU Xia,LIANG Hua-ju~1,SUI Zai-yun~2(Shandong Chest Hospital,Ji′nan 250014;1.Institute of Endemic Disease of Shandong,Ji′nan,250014;2.Institute of TCM of Shandong,Ji′nan,250014);Influence of herbal iodine on apoptosis of testicle tissue in rat[J];Qilu Pharmaceutical Affairs;2006-09
4 LI Yu shu 1,JIN Ying 1,TENG Wei ping 1,SHAN Zhong yan 1,GUAN Hai xia 1,HU Feng nan 1,HAN Ying chao 2,HE Li 3(1 Department of Endocrinology,The First Affiliated Hospital of China Medical University,Shenyang 110001;2 Workers' Hospital of;The Comparative Screening for Thyroid Autoantibodies in Areas with Different Iodine Intakes[J];Shanghai J.of Immunology;2002-02
5 Yi Muqing;Xia Yiming;Tian Yuan (Inst.of Nutrition and Food Hygiene,Chinese Academy of Preventive Medicine,Beijing 100050,China);Effects of selenium and iodine on glutathione peroxidase activity and thyroid hormone metabolism in rats Ⅱ. Effect of selenium and iodine status on thyroid hormone metabolism in rats[J];JOURNAL OF HYGIENE RESEARCH;1995-03
6 Wei Tang,Chao Liu,Yue Jia,Cui-Ping Liu,You-Wen Qin,Guo-Liang Lü,Xin Wang,M in Sun,Xiao-Dong Mao,Department of Endocrinology, First Affiliated Hospital,N anjing Medical University,Nanjing 210029,Jiangsu Provine,China Dong-Ping Guo☆,Department of Pathophysiology,Nanjing Medical University,Nanj ing 210029,Jiangsu Province,China;Relationship between the recovery of immunological function and interleukin-10 gene transfection[J];Chinese Journal of Clinical Rehabilitation;2003-27
7 YL Zheng, Y Xu and JF Lin (FuJian Institute of Medical Science, Fuzhou 350001);IMMUNOSUPPRESIVE EFFECTS OF WILFORTRINE AND EUONINE[J];Acta Pharmaceutica Sinica;1989-08
8 HUA Chuan 1, CHEN Ru-quan 2(1. Department of Surgery,the First Clinical Medicine College Nanjing University of Traditional Chinese Medicine,Nanjing 210029, China ;2. Department of Internal Medicine,Hubei Hospital of Traditional Chinese Medicine,Wuhan 430061, China );Effects of Qijianxiaoyingtang to Mice Thyroiditis on Apoptosis and Ultrastructure[J];Herald of Medicine;2003-09
9 Wang Guangya, Zhou Ruihua, Sun Shuzhuang, Yin Taian, Liu Shengjie, and Yang Guangqi(Institute of Health, Chinese Academy of Medical Sciences, Beijing);METHODS OF FLUORIMETRIC DETERMINATION OF TRACE AMOUNT OF SELENIUM IN BIOLOGICAL MATERIALS,WATER AND SOIL 1.DETERMINATION OF SELENIUM IN HAIR,BLOOD AND URINE[J];Acta Nutrimenta Sinica;1985-01
10 YAO Jun-xia, YI Jian-hua, ZHU Li-guo, et al . (Department of Pathology,Yunyang Medical College,Shiyan 442000,Hubei,China);Significance of Detection of Apoptotic Cells in Endemic Goiter[J];Journal of Yunyang Medical College;2001-01
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 ZHANG Xiongfei,PAN Daobo Department of Anesthesiology,the First People′s Municipal Hospital of Changde,Hunan Province,Changde 415000,China;Effects of Penehyclidine Hydrochloride on apoptosis of myocardial cells induced by ischemia-reperfusion of bi-hind limbs in rats[J];China Medical Herald;2011-18
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 WU Yijie *,XIE Fukang,CAI Li,et al. *Department of Endocrinology,Shanghai First People's Hospital,Shanghai 200080;Effect of increasing iodine intake on incidence of hyperthyroidism[J];CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM;2000-03
2 JIN Ying *,TENG Weiping,YUAN Bai, et al. *Department of Endocrinology,The First Affiliated Hospital, China Medical University,Shenyang 110001;Thyroid autoimmunity in members from multiplex families with Graves' disease and effect of iodine intake on its incidence[J];Chinese Journal of Endocrinology and Metabolism;2001-02
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved