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《Chinese Journal of Information on Traditional Chinese Medicine》 2008-03
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Effect of Berberine on Islet β-cell Function in Type 2 Diabetes Mellitus (Damp-Heat Type)

LIU Hong-ying1, HU Qi-ming2 (1.Jiangxi College of TCM, Nanchang 330006, China;2.The Affiliated Hospital of Jiangxi College of TCM, Nanchang 330006, China)  
Objective To observe the effect of berberine to islet β-cell function in type 2 diabetes mellitus (damp-heat type). Methods 60 patients with type 2 diabetes mellitus (damp-heat type) were randomly divided into 2 groups, under basic treatment of 2 weeks with metformin, the treatment group was given berberine. After 8 weeks, the changes in the levels of blood glucose, insulin, HbA1c, CRP and the grade of traditional Chinese medicine individual event symptom and general integral symptom were observed. Apply the formular to evaluate the pancreas's function. Results Each group had notable difference before and after the experiment in many aspects, especially in treatment group. There was a notable difference in 2 groups. Conclusion Berberine has obvious effect on increasing insulin releasing level, improving insulin sensibility, lightening insulin resistance and improving islet β-cell function.
【CateGory Index】: R259.871
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【Citations】
Chinese Journal Full-text Database 1 Hits
1 Ni Yanxia 208 Hospital,PLA;Therapeutic Effect of Berberine on 60 Patients with Type Ⅱ Diabetes Mellitus and Experimental Research[J];;1988-12
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 YOU Su,LIU Bo.The Second Affiliated Hospital of Ji'nan University,Shenzhen People's Hospital,Shenzhen 518020,China;Effect of Short-term Application of Berberine on Excretion of Fibrin Degradation Product in Urine in Type 2 Diabetics[J];Chinese General Practice;2008-13
2 GAO Qing-yuan,CHEN San-mei.Department of Nursing,Changde Vocational Technical College,Changde 415000,China;Effect of berberine on the expression of oxLDL,LPL in alveolar and peritoneal macrophages in diabetic rats[J];Chinese Journal of Cardiovascular Medicine;2008-04
3 CHEN San-mei,XU Min,WANG Fang,et al.Medical College, Shaoxing University,Zhejiang Shaoxing 312000,China;Effect of berberine treatment on the expressions of oxLDL,CD36 and PPARγ of macrophages from diabetic rats[J];Chinese Journal of Diabetes;2008-07
4 XU Lijun1,LU Fuer1,WEI Shichao2,et al1Institute of Integrated Traditional Chinese and Western Medicine,2Department of Pharmacology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030;Comparison of Therapeutic Effects between 8-Hydroxydihydroberberine and Berberine Hydrochlorde on Type 2 Diabetes Mellitus in Rats[J];Research of Integrated Traditional Chinese and West Medicine;2009-04
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Jiwu CHAI Xiaoshu;Analysis of Nuclear Skeletal Imaging of Primary Liver Cancer Patients with Bone Metastasis and Exploration of Its Syndrome Patterns[J];Journal of New Chinese Medicine;2008-06
2 CHEN Caiying1,CHEN Qun2,TANG Yongxiang2,LIN Xuejuan3,WANG Xiaoling4(1.Student's Affair Department,Guangzhou University of TCM,Guangzhou 510405 Guangdong,China;2.College of Basic Medicine,Guangzhou University of TCM,Guangzhou 510405 Guangdong,China;3.Doctoral Student,Guangzhou University of TCM,Guangzhou 510405 Guangdong,China; 4.The First Affiliated Hospital,Guangzhou University of TCM,Guangzhou 510405 Guangdong,China);Changes of Plasma Von Willebrand Factor Content in Chronic Obstructive Pulmonary Disease and Late Lung Cancer Patients with Qi Deficiency[J];Journal of Guangzhou University of Traditional Chinese Medicine;2008-02
3 CHEN Peiqiong1,JIN Hongyan2,TIAN Guangjun1,CHI Xiaoling1,CHEN Jinfeng3(1.The Second Clinical Medical College,Guangzhou University of TCM,Guangzhou 510405 Guangdong,China; 2.Postgraduate Student of Grade 2005,Guangzhou University of TCM,Guangzhou 510405 Guangdong,China; 3.Foshan Hospital of TCM,Foshan 528000 Guangdong,China);Correlation of Helicobacter Pylori Infection in Liver Cirrhosis of Different Syndrome Patterns with Blood Ammonia Level[J];Journal of Guangzhou University of Traditional Chinese Medicine;2008-02
4 XIE Guiquan1, LEI Tianxiang2, ZHONG Yunliang3,YU Junwen4, YI Tiegang5, LI Yanlin6(1.The First Affiliated Hospital, Guangzhou University of TCM, Guangzhou 510405 Guangdong, China;2. The Second Provincial Hospital of TCM, Guangzhou 510095 Guangdong, China;3. Guangzhou University of TCM, Guangzhou 510405 Guangdong, China;4. Foshan Hospital of TCM, Foshan 528000 Guangdong, China;5. Shenzhen Hospital of TCM, Shenzhen 518033 Guangdong, China;6. Zhongshan Hospital of TCM, Zhongshan 528400 Guangdong, China);Analysis of Traditional Chinese Medical Syndromes and Syndrome Patterns in Diabetic Nephropathy[J];Journal of Guangzhou University of Traditional Chinese Medicine;2008-04
5 Sun Lianghua Li Qun Wang Shu-qing Ma Chuanxiang Zhang Yuanyuan The Affiliated Hospital of Weifang Medical College(Weifang Shandong 261031,China);Research on the Relationship between PCNA and the TCM Differentiation Typing of CAG[J];Journal of Sichuan of Traditional Chinese Medicine;2008-05
6 GAO Yan-yan,YANG Li-bo,JIANG Dong-qing,et al;Study of factors correlated with the change of serumamylin level in patients with type 2diabetes mellitus[J];Shandong Medical Journal;2005-25
7 LIU Bao-shan~1,WANG Chang-chun~2,YING Feng-bo~3,PANG Zong-ran~1(1.Tianjin University of TCM,Tianjin 300193,China;2.Hebei Normal University,Shijiazhuang 050016,China;3.Affiliated Hospital of Chengde Medical College,Chengde 067000,China);Effect of capsule with four-methods-associated-application on the A,B cells in the pancreatic islet of the diabetic rats[J];Shandong Journal of Traditional Chinese Medicine;2006-05
8 TIAN Jing-yan, ZHANG Hong-li, GU Yang-yun, LI Feng-ying, XU Jia, WANG Xiao, LUO Tian-hong, LI Guo, LUO Min (Department of Endocrinology and Metabolism, Shanghai Institute of Endocrinology and Metabolism, Shanghai Clinical Center of Endocrine and Metabolic Diseases, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China);Effect of Amylin on Secretion of Insulin and Glucagon in Rats[J];Journal of Shanghai Jiaotong University(Medical Science);2006-08
9 CHEN Wei, YU Mao-hua, LI Yi-ming△(Department of Geriatrics, Huashan Hospital, Fudan University, Shanghai 200040, China);Effects of astragalus polysaccharides on ultrastructure and oxidation/apoptosis related cytokines′ gene expression of non-obese diabetic mice′s islets[J];Fudan University Journal of Medical Sciences;2007-02
10 ZHANG Yun-yun ZHANG Hai-mei GUO De-ying WEI Xin LIN Bai-rongYueyang Hospital of Integrative Chinese & Western Medicine Affiliated to Shanghai University of Traditional Chinese Medicine;Body Constitution Characteristics of Ischemic Stroke in 168 Cases[J];Shanghai Journal of Traditional Chinese Medicine;2008-02
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