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Experimental Study on Anti-inflammatory Effect of Water-extract of Breynia fruticosa

PENG Wei-wen,TAN Yong-yi,MEI Quan-xi,DAI Wei-bo(Zhongshan Hospital,Guangzhou University of TCM,Zhongshan 528401 Guangdong,China)  
Objective To investigate the anti-inflammatory effect of water-extract of Breynia fruticosa,and to provide scientific experiment evidence for clinical applications.Methods Various inflammatory models,including the ear edema induced by xylene in mice,the increase of capillary permeability induced by acetic acid in mice were used to explore the anti-inflammatory of water-extract of Breynia fruticosa.Results Compared with control group,high and low doses of Breynia fruticosa could significantly inhibit ear edema,and both doses of Breynia fruticosa could significantly inhibit the increase of capillary permeability.Conclusion The water-extract of Breynia fruticosa has significant anti-inflammatory effect.
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