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《Hereditas(Beijing)》 2005-03
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Growth Differentiation Factor 9 Gene and Its Role in Reproduction

WU Ze-Hui~1, CHU Ming-Xing~2, LI Xue-Wei~1(1. College of Animal Science and Technology, Sichuan Agricultural University, Ya’an 625014, China;2. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100094, China)  
Growth differentiation factor 9 (GDF9) secreted by oocyte is essential for follicular growth and differentiation. This review introduced the structure, function and regulation of GDF9, as well as the cloning and structure, developmental expression, mapping and polymorphism of GDF9 gene. The relationship between GDF9 gene and reproductive performance was also discussed in mammals.
【Fund】: 国家自然科学基金资助项目(批准号:30300248和30140004);; 国家高技术研究发展计划(863计划)资助(课题编号:2002AA211081)~~
【CateGory Index】: Q75
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