Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Hereditas》 2008-01
Add to Favorite Get Latest Update

Research on modular organization of gene regulatory network

WANG Zheng-Hua1, LIU Qi-Jun1,2, ZHU Yun-Ping2 1. National Laboratory For Parallel & Distributed Processing, National University of Deference and Technology, Changsha 410073, China;2. State Key Laboratory of Proteomics, Beijing Proteomics Research Center, Beijing Institute of Radiation Medicine, Beijing 102206, China  
Gene regulatory network is very important for researchers to understand biological processes and gene functions. It can deliver complex information about how could large amount of genes be regulated by transcriptional factors and trans-lated into proteins which can carried out biological functions. Generally, knowledge of network topological structure and organization formation can be used to find the regulatory mechanism of genes in the regulatory network. It can illuminate the local characters of the network and reveal the constructing methods of regulatory network;moreover, it can also analyze regulatory pathway completely and systemically. Now, more and more researchers approbate the hierarchy structure of gene regulatory network:regulatory component, Motif, module and the whole network. Here, we discuss the middle two levels:motif and module. We compared various research results of network organization carried out in recent years, explicated their biology signification and pointed out the existing disadvantages and problems. According these problems, we also bring up some possible research trend. And at last, we discuss the prospect of gene regulatory network modular organization researching work.
【Fund】: 国家重点基础研究发展规划(973计划)项目(编号:2006CB910706、2006CB910800);; 国家高技术研究发展计划项目(863计划)(编号:2006AA02A312);; 国家自然科学基金(编号:30621063 60603054)项目资助~~
【CateGory Index】: Q3
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 2 Hits
1 GUO Zhi-long1,2,JI Zhao-hua1,3,TU Hua-wei1,LIANG Yan-chun1(1.College of Computer Science and Technology,Jilin University,Changchun 130012,China;2.Dalian Huaxin Software Corporation,DaLian 116000,China;3.Inner Mongolia Xing'an Vocational and Technical College,Wulanhaote 137400,China);The Research Content And Data Analysis Methods on the Gene Regulatory Networks[J];Computer Knowledge and Technology;2008-15
2 LIU Qi-Jun1,2,WANG Zheng-hua1,GUO Hao2,SUN Han-chang2,3,LIU Wan-lin2,ZHU Yun-ping2(1.National Laboratory for Parallel and Distributed Processing,Changsha 410073;2.State Key Laboratory of Proteomics,Beijing Proteomics Research Center,Beijing Institute of Radiation Medicine,Beijing 102206;3.Department of Automatic Control,School of Mechatronics and Automation,National University of Defense Technology,Changsha 410073,China);A Novel Method for Measuring the Modularity of Biological Complex Networks[J];Computer Engineering & Science;2010-08
【Co-citations】
Chinese Journal Full-text Database 4 Hits
1 HUANG Hai-bin1,2,YANG Lu-ming1,WANG Jian-xin1,LI Shao-hua1,3 1.School of Information Science and Engineering,Central South University,Changsha 410083,China 2.Department of Mathematics and Computer Science,Yulin Normal College,Yulin,Guangxi 537000,China 3.Department of Computer Science and Technology,Guangdong Commercial College,Guangzhuo 510320,China;On Essential Protein identification based on Minimal Vertex Cover and multi-parameter[J];Computer Engineering and Applications;2008-27
2 HUANG Hai-Bin1,2 YANG Lu-Ming1 WANG Jian-Xin1 LI Shao-Hua1,31. School of Information Science and Engineering, Central South University, Changsha 410083 2. Department of Math- ematics and Computer Science, Yulin Normal College, Yulin 537000 3. Department of Computer Science and Technology, Guangdong Commercial College, Guangzhou 510320;Identification Technique of Essential Nodes in Protein Networks Based on Combined Parameters[J];Acta Automatica Sinica;2008-11
3 HUANG Hai-bin~1,YANG Lu-ming~2,WANG Jian-xin~2,CHEN Jian-er~(2,3), LI Shao-hua~(2,4),DU Xiu-ying~2 (1.Department of Mathematics and Computer Science,Yulin Normal College,YuLin 537000,China) (2.School of Information Science and Engineering,Cental south University,Changsha 410083,China) (3.Department of computer Science,Texas A & M University,College Station,Texas 77843-3112,USA) (4.Department of Computer Science and Technology,Guangdong Commercial College,Guangzhou 510320, China) (5.Library,Yulin Normal College,YuLin 537000,China);Identification of Essential Nodes Based on Topology of a Bionetwork[J];Mathematics in Practice and Theory;2011-07
4 HUANG Hai-bin1,SHAO Ping2(1.Associate Professor,Ph.D,Dept.of Math & Computer Science,Yulin Normal University,Yulin,Guangxi 537000)(2.Professor,Ph.D,Dept.Physics and Information Science,Yulin Normal University,Yulin,Guangxi 537000);Progress of Essential Nodes Identification in Bionetworks Based on Topological Structure[J];Journal of Yulin Normal University(Nature Science);2009-03
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LIN Guoji, JIA Xun, OUYANG Qi △ (Laboratory of Nonlinear Science, School of Physics and Center for Theoretical Biology, Peking University, Beijing 100871, China);Predict SARS infection with the small world network model[J];Journal of Beijing Medical University;2003-S1
2 BAI Hong tao,SUN Ji gui, JIAO Yang, XU Chang qing (College of Computer Science and Technology, Jilin University, Changchun, 130012,China);Implementation and comparison of network optimization algorithms[J];Journal of Changchun Post and Telecommunication Institute;2002-02
3 GONG Ai-yan~1,WU Sheng-xi~1,HU Ren-jian~1,WANG Jian~2(1.Bioengineering College,Chongqing Institute of Technology,Chongqing 400050, China;2.Agricultural Bureau of Chongqing,Chongqing 400015,China);Comparative Study on Fluorescence RT-PCR and RT-PCR Testing Methods for Detecting Avian Influenza Virus in Chickens[J];Journal of Chongqing Institute of Technology;2006-11
4 ZHOU Hui-jie(Ningbo University,Ningbo 315211);Application of Complex Network Theory in Gene Regulatory Networks[J];Journal of Chongqing University of Science and Technology(Natural Sciences Edition);2009-05
5 YU Hui-ting~(1),WU Cheng~(1),LIU Wei-wei~(1),FU Xu-ping~(2),HE Jia~(1*)(1.Department of Health Statistics,Faculty of Health Services,Second Military Medical University,Shanghai 200433,China;2.State Key Laboratory of Genetic Engineering,Institute of Genetics,School of Life Science,Fudan University,Shanghai 200433);Modeling of gene regulatory networks[J];Academic Journal of Second Military Medical University;2006-07
6 ZHANG Guo-wei, SHAO Shi-huang, ZHANG Ying, QI Jin-peng (College of Information Science and Technology, Donghua University, Shanghai, 200051);Boolean Genetic Networks and Its Recent Research[J];Journal of Donghua University(Natural Science);2006-02
7 WANG Hao,HE Hai-yan,YAO Hong-liang,HU Da-wei (Department of Computer Science and Technology, Hefei University of Technology,Hefei 230009,China);IE_-K2:An effective Bayesian method for constructing gene regulatory network[J];Journal of Dalian Maritime University;2008-03
8 GUO Zhi-long1,2,JI Zhao-hua1,3,TU Hua-wei1,LIANG Yan-chun1(1.College of Computer Science and Technology,Jilin University,Changchun 130012,China;2.Dalian Huaxin Software Corporation,DaLian 116000,China;3.Inner Mongolia Xing'an Vocational and Technical College,Wulanhaote 137400,China);The Research Content And Data Analysis Methods on the Gene Regulatory Networks[J];Computer Knowledge and Technology;2008-15
9 LIU Ling,YI Dong(Department of Medical Statistics,College of Preventive Medicine,Third Military Medical University,Chongqing 400038,China);Study on bio-dynamic equation for gene regulation networks[J];Acta Academiae Medicinae Militaris Tertiae;2007-08
10 LI Yan da (Bioinformatics Institute,Tsinghua University,State Key Laboratory of Intelligent Technology and System,Beijing 100084,China);Understanding Genome from Information System Point of View[J];Acta Electronica Sinica;2001-S1
【Secondary References】
Chinese Journal Full-text Database 1 Hits
1 JIN Liyan;HAN Bin;LI Lihua;ZHU Lei;FAN Shuangxi;College of Life Information Science and Instrument Engineering, Hangzhou Dianzi University;;Reconstructing In-Silico Gene Regulatory Network Based on Reproducing Kernel Hilbert Space[J];Acta Biophysica Sinica;2013-07
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved